ArticleBioImpacts : BI2012
Electrochemical impedance spectroscopic sensing of methamphetamine by a specific aptamer.
Article in BioImpacts : BI, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Accelerated aptamer selectionRSC advances · 2025Article
- Wearable Electrochemical Glove-Based Analytical Device (eGAD) for the Detection of Methamphetamine Employing Silver Nanoparticles.Biosensors · 2023Article
- Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers.BioImpacts : BI · 2023Article
- Label-free electrochemical microfluidic biosensors: futuristic point-of-care analytical devices for monitoring diseases.Mikrochimica acta · 2022Review
- Nanomaterial-based aptamer sensors for analysis of illicit drugs and evaluation of drugs consumption for wastewater-based epidemiology.Trends in analytical chemistry : TRAC · 2020Review
- A Bottom-Up Approach for Developing Aptasensors for Abused Drugs: Biosensors in Forensics.Biosensors · 2019Review
- SPR signals enhancement by gold nanorods for cell surface marker detection.BioImpacts : BI · 2019Article
- Practical Application of Aptamer-Based Biosensors in Detection of Low Molecular Weight Pollutants in Water Sources.Molecules (Basel, Switzerland) · 2018Review
- Microfluidic paper-based analytical devices (µPADs) for fast and ultrasensitive sensing of biomarkers and monitoring of diseases.BioImpacts : BI · 2018Article
- A compact microfluidic chip with integrated impedance biosensor for protein preconcentration and detection.Biomicrofluidics · 2017Article
- Computerized techniques pave the way for drug-drug interaction prediction and interpretation.BioImpacts : BI · 2016Review
- Label-free electrochemical diagnosis of viral antigens with genetically engineered fusion protein.Sensors (Basel, Switzerland) · 2012Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionElectrochemical impedance spectroscopy (EIS) is a simple and highly sensitive technique that can be used for evaluation of the aptamer-target interaction even in a label-free approach.
methodsTo pursue the effectiveness of EIS, in the current study, the folding properties of specific aptamer for methamphetamine (METH) (i.e., aptaMETH) were evaluated in the presence of METH and amphetamine (Amph). Folded and unfolded aptaMETH was mounted on the gold electrode surface and the electron charge transfer was measured by EIS.
resultsThe Ret of methamphetamine-aptaMETH was significantly increased in comparison with other folding conditions, indicating specific detection of METH by aptaMETH.
conclusionBased on these findings, methamphetamine-aptaMETH on the gold electrode surface displayed the most interfacial electrode resistance and thus the most folding situation. This clearly indicates that the aptaMETH can profoundly and specifically pinpoint METH; as a result we suggest utilization of this methodology for fast and cost-effective identification of METH.
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