Evidence map›Paper›PMID 23678071›Full record

ArticleJournal of clinical microbiology2013

Comparative evaluation of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry systems for identification of yeasts of medical importance.

Nicasio Mancini, Elena De Carolis, Laura Infurnari, Antonietta Vella, Nicola Clementi, Luisa Vaccaro, Alberto Ruggeri, Brunella Posteraro, Roberto Burioni, Massimo Clementi and 1 more

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Evaluation of the VITEKEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Candida dubliniensis fungemia in a patient with severe COVID-19: A case report.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2022
    Article
  5. Mass spectrometry in research laboratories and clinical diagnostic: a new era in medical mycology.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Taxonomy and evolution ofComputational and structural biotechnology journal · 2018
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Evaluation of the Bruker Biotyper and VITEK MS MALDI-TOF MS systems for the identification of unusual and/or difficult-to-identify microorganisms isolated from clinical specimens.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
    Article
  20. Comparison and optimization of two MALDI-TOF MS platforms for the identification of medically relevant yeast species.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicasio ManciniLaboratorio di Microbiologia e Virologia, Università "Vita-Salute" San Raffaele, Milan, Italy. mancini.nicasio@hsr.it
Elena De Carolis
Laura Infurnari
Antonietta Vella
Nicola Clementi
Luisa Vaccaro
Alberto Ruggeri
Brunella Posteraro
Roberto Burioni
Massimo Clementi
Maurizio Sanguinetti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the first comparative evaluation between the Bruker Biotyper MS (BMS) and the Vitek MS (VMS) for the identification of yeasts. The rate of correct identifications at the species level was comparable using the commercial databases (89.8% versus 84.3%; P = 0.712), but higher for BMS using an in-house-extended database (100% versus 84.3%; P = 0.245). Importantly, the rate of misidentification was significantly higher for VMS (1% versus 12.1%; P < 0.0001), including the rate of major errors (0% versus 4.5%; P = 0.0036).

Indexed as

Diagnostic ErrorsHumansMicrobiological TechniquesMycological Typing TechniquesMycologyMycosesSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTime FactorsYeasts

Identifiers

PMID23678071
PMCPMC3697679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.