ArticleAnnals of surgery2013
Acute kidney injury, renal function, and the elderly obese surgical patient: a matched case-control study.
Article in Annals of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 60 citations in OpenAlex.
- Dynamic Changes in Serum Neutrophil Gelatinase-Associated Lipocalin for Discrimination of Creatinine-Defined Acute Kidney Injury After Laparoscopic Sleeve Gastrectomy: A Prospective Observational Cohort Study.Journal of clinical medicine · 2026Article
- Obesity Correlates With 90-Day Postoperative Complications but Not 5-Year Retearing Rates After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2025Article
- Differential Pattern of Obesity in Total Hip and Knee Arthroplasty Candidates.Physiotherapy Canada. Physiotherapie Canada · 2025Article
- Incidence and predictors of acute kidney injury after elective surgery for lumbar degenerative disease: A 13-year analysis of the US Nationwide Inpatient Sample.Journal of the Chinese Medical Association : JCMA · 2024Article
- Effect of potential risk factors on renal functions in simultaneous bilateral total knee arthroplasty.Frontiers in surgery · 2024Article
- The Effectiveness of Nutritional Strategies in the Treatment and Management of Obesity: A Systematic Review.Cureus · 2023Review
- Post-operative complications of total knee arthroplasty in patients with hypertension.International orthopaedics · 2023Article
- Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.Aging · 2022Article
- Intraoperative Monitoring of the Obese Patient Undergoing Surgery: A Narrative Review.Advances in therapy · 2021Review
- Incidence and Predictors of Acute Kidney Injury in Patients Undergoing Elective Hepatic Resection for Malignant Tumors: A 3-year Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.BMC complementary medicine and therapies · 2021Article
- Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.Frontiers in medicine · 2021Article
- Relationship of body mass index, serum creatine kinase, and acute kidney injury after severe trauma.The journal of trauma and acute care surgery · 2020Article
- Artificial Intelligence in Acute Kidney Injury Risk Prediction.Journal of clinical medicine · 2020Review
- Article
- Low, rather than High, Body Mass Index Is a Risk Factor for Acute Kidney Injury in Multiethnic Asian Patients: A Retrospective Observational Study.International journal of nephrology · 2018Article
- Surgical Technical Evidence Review for Elective Total Joint Replacement Conducted for the AHRQ Safety Program for Improving Surgical Care and Recovery.Geriatric orthopaedic surgery & rehabilitation · 2018Review
- Acute kidney injury following primary hip and knee arthroplasty surgery.Annals of the Royal College of Surgeons of England · 2017Article
- Impact of body mass index on risk of acute kidney injury and mortality in elderly patients undergoing hip fracture surgery.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Obesity, acute kidney injury and outcome of critical illness.International urology and nephrology · 2017Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo investigate the association between obesity and perioperative acute kidney injury (AKI), controlling for preoperative kidney dysfunction.
backgroundMore than 30% of patients older than 60 years are obese and, therefore, at risk for kidney disease. Postoperative AKI is a significant problem.
methodsWe performed a matched case-control study of patients enrolled in the Obesity and Surgical Outcomes Study, using data of Medicare claims enriched with detailed chart review. Each AKI patient was matched with a non-AKI control similar in procedure type, age, sex, race, emergency status, transfer status, baseline estimated glomerular filtration rate, admission APACHE score, and the risk of death score with fine balance on hospitals.
resultsWe identified 514 AKI cases and 694 control patients. Of the cases, 180 (35%) followed orthopedic procedures and 334 (65%) followed colon or thoracic surgery. After matching, obese patients undergoing a surgical procedure demonstrated a 65% increase in odds of AKI within 30 days from admission (odds ratio = 1.65, P < 0.005) when compared with the nonobese patients. After adjustment for potential confounders, the odds of postoperative AKI remained elevated in the elderly obese (odds ratio = 1.68, P = 0.01.)
conclusions: Obesity is an independent risk factor for postoperative AKI in patients older than 65 years. Efforts to optimize kidney function preoperatively should be employed in this at-risk population along with keen monitoring and maintenance of intraoperative hemodynamics. When subtle reductions in urine output or a rising creatinine are observed postoperatively, timely clinical investigation is warranted to maximize renal recovery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.