Evidence map›Paper›PMID 23676294›Full record

ArticleJournal of the American Heart Association2013

Improved survival after heart failure: a community-based perspective.

Samuel W Joffe, Kristy Webster, David D McManus, Michael S Kiernan, Darleen Lessard, Jorge Yarzebski, Chad Darling, Joel M Gore, Robert J Goldberg

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samuel W JoffeDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Kristy Webster
David D McManus
Michael S Kiernan
Darleen Lessard
Jorge Yarzebski
Chad Darling
Joel M Gore
Robert J Goldberg

Funding

University of Massachusetts Center for Clinical and Translational ScienceUL1TR000161 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LUZURIAGA, KATHERINE F · 2012 to 2015
$11.0M
Monitoring Community Trends in Heart FailureR37HL069874 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GOLDBERG, ROBERT JOEL · 2002 to 2011
$6.7M
TRACE-COREU01HL105268 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2010 to 2013
$5.8M
University of Massachusetts Center for Clinical and Translational ScienceKL2RR031981 · NCRR · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SULLIVAN, JOHN LEWIS · 2010 to 2011
$1.2M
Acute Decompensated Heart Failure: Treatment Timing and Effects on OutcomesK23HL101991 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DARLING, CHAD ERIC · 2010 to 2014
$668k
NCATS NIH HHS UL1 TR000161NCRR NIH HHS KL2 RR031981NCRR NIH HHS KL2RR031981NHLBI NIH HHS 1U01HL105268NHLBI NIH HHS K23 HL101991NHLBI NIH HHS R37 HL069874NHLBI NIH HHS R37 HL69874NHLBI NIH HHS U01 HL105268
6 · The paper itself

Abstract

backgroundHeart failure is a highly prevalent, morbid, and costly disease with a poor long-term prognosis. Evidence-based therapies utilized over the past 2 decades hold the promise of improved outcomes, yet few contemporary studies have examined survival trends in patients with acute heart failure. The primary objective of this population-based study was to describe trends in short- and long-term survival in patients hospitalized with acute decompensated heart failure (ADHF). A secondary objective was to examine patient characteristics associated with decreased long-term survival. METHODS AND

resultsWe reviewed the medical records of 9748 patients hospitalized with ADHF at all 11 medical centers in central Massachusetts during 1995, 2000, 2002, and 2004. Patients hospitalized with ADHF were more likely to be elderly and to have been diagnosed with multiple comorbidities in 2004 compared with 1995. Over this period, survival was significantly improved in-hospital, and at 1, 2, and 5 years postdischarge. Five-year survival rates increased from 20% in 1995 to 29% in 2004. Although survival improved substantially over time, older patients and patients with chronic kidney disease, chronic obstructive pulmonary disease, anemia, low body mass index, and low blood pressures had consistently lower postdischarge survival rates than patients without these comorbidities.

conclusionBetween 1995 and 2004, patients hospitalized with ADHF have become older and increasingly comorbid. Although there has been a significant improvement in survival among these patients, their long-term prognosis remains poor, as fewer than 1 in 3 patients hospitalized with ADHF in 2004 survived more than 5 years.

Indexed as

AgedAged, 80 and overFemaleHeart FailureHumansMaleMiddle AgedPatient DischargePrognosisResidence CharacteristicsSurvival RateTime Factorsacute heart failurepopulation surveillancesurvivaltime trends

Identifiers

PMID23676294
PMCPMC3698761

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.