ArticleBMC medicine2013
Depression as a risk factor for adverse outcomes in coronary heart disease.
Article in BMC medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- The prevalence of depression among adolescent with HIV/AIDS: a systematic review and meta-analysis.AIDS research and therapy · 2021Pooled it
- The Prevalence of Suicidal Ideation and Attempt Among Young People with HIV/AIDS: a Systematic Review and Meta-Analysis.The Psychiatric quarterly · 2020Pooled it
- Social determinants of depression and suicidal behaviour in the Caribbean: a systematic review.BMC public health · 2017Pooled it
- The contribution of major depression to the global burden of ischemic heart disease: a comparative risk assessment.BMC medicine · 2013Pooled it
- Integration of Behavioral Health by Community Health Workers Into a Lifestyle Intervention That Addresses Reduction of Risk for Cardiovascular Disease in Rural Communities.Preventing chronic disease · 2026Article
- Association between specific neuroticism symptoms and cardiovascular disease: insights from genetic analysis.European archives of psychiatry and clinical neuroscience · 2026Article
- Novel Virtual Reality Intervention for Stress Reduction Among Patients With or at Risk for Cardiovascular Disease: Mixed Methods Pilot Study.JMIR cardio · 2025Article
- Depression and Coronary Artery Disease-Where We Stand?Journal of clinical medicine · 2025Review
- PTSD, Comorbidities, Gender, and Increased Risk of Cardiovascular Disease in a Large Military Cohort.medRxiv : the preprint server for health sciences · 2024Article
- The Role of Brain-Derived Neurotrophic Factor (BDNF) in Depression and Cardiovascular Disease: A Systematic Review.Life (Basel, Switzerland) · 2023Review
- Depression and Physical activity among cardiac patients undergone cardiac events: a correlational study.Investigacion y educacion en enfermeria · 2023Article
- Post-traumatic stress disorder (PTSD) as a systemic disorder: Pathways to cardiovascular disease.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022Review
- Emergency Departments as Care Providers for Patients with Cardiac Ambulatory Care Sensitive and Mental Health Conditions: Qualitative Interview and Focus Group Study with Patients and Physicians.International journal of environmental research and public health · 2022Article
- Association Between Depression and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy.Journal of the American Heart Association · 2021Article
- Longitudinal Changes in Depressive Symptoms and Risks of Cardiovascular Disease and All-Cause Mortality: A Nationwide Population-Based Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Diet, Stress and Mental Health.Nutrients · 2020Review
- Depression and coronary heart disease: 2018 position paper of the ESC working group on coronary pathophysiology and microcirculation.European heart journal · 2020Article
- Upregulation of microRNA-204 improves insulin resistance of polycystic ovarian syndrome via inhibition of HMGB1 and the inactivation of the TLR4/NF-κB pathway.Cell cycle (Georgetown, Tex.) · 2020Article
- Article
- Down-regulation of microRNA-429 alleviates myocardial injury of rats with coronary heart disease.Cell cycle (Georgetown, Tex.) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression is firmly established as an independent predictor of mortality and cardiac morbidity in patients with coronary heart disease (CHD). However, it has been difficult to determine whether it is a causal risk factor, and whether treatment of depression can improve cardiac outcomes. In addition, research on biobehavioral mechanisms has not yet produced a definitive causal model of the relationship between depression and cardiac outcomes. DISCUSSION: Key challenges in this line of research concern the measurement of depression, the definition and relevance of certain subtypes of depression, the temporal relationship between depression and CHD, underlying biobehavioral mechanisms, and depression treatment efficacy. SUMMARY: This article examines some of the methodological challenges that will have to be overcome in order to determine whether depression should be regarded as a key target of secondary prevention in CHD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.