Evidence map›Paper›PMID 23674933›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2013

Evaluation of drug-induced sleep endoscopy as a patient selection tool for implanted upper airway stimulation for obstructive sleep apnea.

Olivier M Vanderveken, Joachim T Maurer, Winfried Hohenhorst, Evert Hamans, Ho-Sheng Lin, Anneclaire V Vroegop, Clemens Anders, Nico de Vries, Paul H Van de Heyning

3 registry-linked trialsAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 152 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 8 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06372847 narecruitingnot on this mapstarted 2025, after this paper: background citation

Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on the Site of Collapse During DISE

TypeinterventionalSponsorUniversity Hospital, AntwerpRan2025 to 2028Enrolled58ConditionsObstructive Sleep ApneaArmsHypoglossal nerve stimulation implant, Polysomnography, Drug-induced sleep endoscopy (DISE)
NCT07132307 narecruitingnot on this mapstarted 2025, after this paper: background citation

Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through

TypeinterventionalSponsorWashington University School of MedicineRan2025 to 2027Enrolled30ConditionsObstructive Sleep ApneaArmsMandibular advancement device (MAD)
NCT07337239 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-induced Sleep Endoscopy

TypeinterventionalSponsorUniversity Hospital, AntwerpRan2026 to 2027Enrolled21ConditionsObstructive Sleep ApneaArmsAdditional measurements during clinical standard follow-up drug-induced sleep endoscopy (DISE)
3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 8 syntheses or guidelines pooled it, 327 citations in OpenAlex.

  1. Airway Changes After Sleep Apnea Surgery Using Drug-Induced Sedation Endoscopy: A Systematic Review and Meta-analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Pooled it
  7. Guideline
  8. Pooled it
  9. Trial
  10. Relation between arousability and outcome of upper airway stimulation in the Stimulation for Apnea Reduction (STAR) Trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Trial
  11. Trial
  12. The importance of drug-induced sedation endoscopy (D.I.S.E.) techniques in surgical decision making: conventional versus target controlled infusion techniques-a prospective randomized controlled study and a retrospective surgical outcomes analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017
    Trial
  13. Article
  14. Review
  15. Article
  16. Article
  17. Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024).World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  18. Article
  19. Article
  20. The upper airway in obstructive sleep apnoea: state of the art.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review

92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Olivier M VandervekenDepartment of ENT, Head and Neck Surgery, Antwerp University Hospital, Edegem, Antwerp, Belgium. olivier.vanderveken@uza.be
Joachim T Maurer
Winfried Hohenhorst
Evert Hamans
Ho-Sheng Lin
Anneclaire V Vroegop
Clemens Anders
Nico de Vries
Paul H Van de Heyning
University of Antwerp · BEHeidelberg University · DEHelios Universitätsklinikum Wuppertal · DESint Lucas Andreas Hospital · NLWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesTo study the possible predictive value of drug-induced sleep endoscopy (DISE) in assessing therapeutic response to implanted upper airway stimulation (UAS) for obstructive sleep apnea (OSA).

methodsDuring DISE, artificial sleep is induced by midazolam and/or propofol, and the pharyngeal collapse patterns are visualized using a flexible fiberoptic nasopharyngoscope. The level (palate, oropharynx, tongue base, hypopharynx/epiglottis), the direction (anteroposterior, concentric, lateral), and the degree of collapse (none, partial, or complete) were scored in a standard fashion.

resultsWe report on the correlation between DISE results and therapy response in 21 OSA patients (apnea-hypopnea index [AHI] 38.5 ± 11.8/h; body mass index [BMI] 28 ± 2 kg/m(2), age 55 ± 11 y, 20 male/1 female) who underwent DISE before implantation of a UAS system. Statistical analysis revealed a significantly better outcome with UAS in patients (n = 16) without palatal complete concentric collapse (CCC), reducing AHI from 37.6 ± 11.4/h at baseline to 11.1 ± 12.0/h with UAS (p < 0.001). No statistical difference was noted in AHI or BMI at baseline between the patients with and without palatal CCC. In addition, no predictive value was found for the other DISE collapse patterns documented.

conclusionsThe absence of palatal CCC during DISE may predict therapeutic success with implanted UAS therapy. DISE can be recommended as a patient selection tool for implanted UAS to treat OSA.

Indexed as

Patient SelectionAirway ObstructionElectric StimulationEndoscopyFemaleFiber Optic TechnologyHumansHypnotics and SedativesHypoglossal NerveMaleMidazolamMiddle AgedPharynxPolysomnographyPropofolSleep Apnea, ObstructiveHypnotics and SedativesMidazolamPropofolElectrical stimulationhypoglossal nerveneuromodulationobstructive sleep apnea hypopnea syndromepredictionsleep disordered breathingsnoring

Identifiers

PMID23674933
PMCPMC3629316
OpenAlexW2081724189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.