ArticleInteractive cardiovascular and thoracic surgery2013
The role of surgical lung biopsy in the management of interstitial lung disease: experience from a single institution in the UK.
Article in Interactive cardiovascular and thoracic surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Yield and safety of different biopsy types in interstitial lung disease: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Diagnosis of Hypersensitivity Pneumonitis in Adults. An Official ATS/JRS/ALAT Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2020Guideline
- Feasibility and safety of transbronchial lung cryobiopsy and mediastinal lymph node cryobiopsy: Experience from a resource limited African setting.African journal of thoracic and critical care medicine · 2025Article
- The cool new kid on the block: Lung cryobiopsy.African journal of thoracic and critical care medicine · 2023Article
- Impact of Lung Biopsy Information on Treatment Strategy of Patients with Interstitial Lung Diseases: The Glass Is Half Full.Annals of the American Thoracic Society · 2022Article
- Outcomes for Elective Open and Thoracoscopic Surgical Lung Biopsies in the United States and Temporal Trends.Mayo Clinic proceedings. Innovations, quality & outcomes · 2022Article
- Pulmonary granulomatosis of genetic origin.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Morphological and molecular motifs of fibrosing pulmonary injury patterns.The journal of pathology. Clinical research · 2019Article
- Utility of Flexible Bronchoscopic Cryobiopsy for Diagnosis of Diffuse Parenchymal Lung Diseases.Journal of bronchology & interventional pulmonology · 2018Article
- The Lung in Primary Immunodeficiencies: New Concepts in Infection and Inflammation.Frontiers in immunology · 2018Review
- Airway-centered interstitial fibrosis - an under-recognized subtype of diffuse parenchymal lung diseases.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2018Article
- Open lung biopsy performed in idiopathic pulmonary fibrosis is a safe procedure.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2017Article
- Assessing the Safety and Clinical Impact of Thoracoscopic Lung Biopsy in Patients with Interstitial Lung Disease.Journal of clinical and diagnostic research : JCDR · 2017Article
- A Review of the Multidisciplinary Diagnosis of Interstitial Lung Diseases: A Retrospective Analysis in a Single UK Specialist Centre.Journal of clinical medicine · 2016Article
- Pleuroparenchymal fibroelastosis: role of high-resolution computed tomography (HRCT) and CT-guided transthoracic core lung biopsy.Insights into imaging · 2016Article
- Videothoracoscopy-assisted surgical lung biopsy for interstitial lung diseases.General thoracic and cardiovascular surgery · 2014Article
- Invited commentary: Videothoracoscopy-assisted surgical lung biopsy for interstitial lung diseases.General thoracic and cardiovascular surgery · 2014Article
- The efficacy of video-assisted thoracoscopic surgery lung biopsies in patients with Interstitial Lung Disease: a retrospective study of 66 patients.Journal of cardiothoracic surgery · 2014Article
- Lung surgery in interstitial lung disease-a safe and useful procedure?Journal of thoracic disease · 2013Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesInterstitial lung disease (ILD) includes a wide spectrum of pulmonary pathologies. The role of surgical lung biopsy (SLB) in the diagnosis of ILD is still controversial. The purpose of this study was to ascertain whether SLB is worthwhile in the management of ILD.
methodsOne hundred and three patients underwent SLB for ILD from April 2008 to March 2010 at a single institution. Outcomes included patient demographics, preoperative investigations, preoperative diagnosis and treatment, surgical approach, number and site of biopsies, complications, length of postoperative stay and postoperative pathological diagnosis and treatment.
resultsFifty-one (49.6%) patients were male and 52 (50.4%) were female. The median age was 58 (range 26-78). Major complications were seen in 7 patients (6.8%). Five patients (4.9%) died within 30 days following surgery. Definitive pathological diagnosis (DPD) was reached in 72 (69.9%) patients, whereas no DPD was achieved in 31 (30.1%). Within the group of patients who received DPD, this differed from the clinical diagnosis in 53 patients (51.5%), and was concordant in 19 (18.4%). The DPD was helpful in guiding the management of 47 patients (45.6%), who had a change in their treatment following the procedure. The median hospital stay was 4 days (range 2-42 days).
conclusionsSLB is a well-recognized procedure. Although it provides a diagnosis for the majority of patients, in our series SLB was inconclusive in a considerable number of cases and did not lead to a therapeutic change for more than half of all patients. Furthermore, SLB is not without risk and can be associated with a prolonged hospital stay. We believe that SLB should be performed in a select group of patients with ILD after discussion by a multidisciplinary panel.
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