SynthesisHuman brain mapping2014
The functional neuroanatomy of male psychosexual and physiosexual arousal: a quantitative meta-analysis.
Synthesis in Human brain mapping, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Cognitive profiles of paedophilic behaviour: a meta-analytic and systematic review of developmental vs acquired forms.Frontiers in psychiatry · 2025Pooled it
- Systemic Symptoms in Huntington's Disease: A Comprehensive Review.Movement disorders clinical practice · 2024Pooled it
- Neural substrates of sexual arousal are not sex dependent.Proceedings of the National Academy of Sciences of the United States of America · 2019Pooled it
- The neural basis of sex differences in sexual behavior: A quantitative meta-analysis.Frontiers in neuroendocrinology · 2016Pooled it
- Association of sexual dysfunctions according to DSM-5 criteria with structural brain differences in women and men from the Hamburg City Health Study.Dialogues in clinical neuroscience · 2026Article
- Rethinking sexual response: are erogenous zones-including nipple stimulation-more than secondary stimuli? A meta-analysis.Sexual medicine · 2026Article
- Article
- Persistent appetitive memory in problematic pornography users.Journal of behavioral addictions · 2026Article
- Altered gray matter morphometry in psychogenic erectile dysfunction patients: A Surface-based morphometry study.Scientific reports · 2025Article
- Neuroaffective Processing of Sexually Relevant Images in Hetero- and Homosexual Women and Men: Subjective, Pupillometric, and Magnetoencephalographic Correlates.Psychophysiology · 2025Article
- Appetitive conditioning with pornographic stimuli elicits stronger activation in reward regions than monetary and gaming-related stimuli.Human brain mapping · 2024Article
- Electroacupuncture for psychogenic erectile dysfunction: A resting-state functional magnetic resonance imaging study exploring the alteration of fractional amplitude of low frequency fluctuation.Frontiers in human neuroscience · 2023Article
- Neurophysiology of male sexual arousal-Behavioral perspective.Frontiers in behavioral neuroscience · 2023Review
- Functional Connectivity of Nucleus Accumbens Is Associated with Lifelong Premature Ejaculation in Male Adults : A Resting-state fMRI Study.Clinical neuroradiology · 2022Article
- Distended Seminal Vesicles Are Involved in Specific Cerebral Sexual Arousal: A Pilot Study Using Functional Brain Imaging in Young Healthy Men.European urology open science · 2022Article
- A psychophysical and neuroimaging analysis of genital hedonic sensation in men.Scientific reports · 2022Article
- Convergent and Divergent Structural Connectivity of Brain White Matter Network Between Patients With Erectile Dysfunction and Premature Ejaculation: A Graph Theory Analysis Study.Frontiers in neurology · 2022Article
- Smaller volume and altered functional connectivity of the amygdala in patients with lifelong premature ejaculation.European radiology · 2021Article
- High Frequency of Concomitant Bladder, Bowel, and Sexual Symptoms in Huntington's Disease: A Self-Reported Questionnaire Study.Journal of personalized medicine · 2021Article
- Sexual incentive delay in the scanner: Sexual cue and reward processing, and links to problematic porn consumption and sexual motivation.Journal of behavioral addictions · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Reproductive behavior is mandatory for conservation of species and mediated by a state of sexual arousal (SA), involving both complex mental processes and bodily reactions. An early neurobehavioral model of SA proposes cognitive, emotional, motivational, and autonomic components. In a comprehensive quantitative meta-analysis on previous neuroimaging findings, we provide here evidence for distinct brain networks underlying psychosexual and physiosexual arousal. Psychosexual (i.e., mental sexual) arousal recruits brain areas crucial for cognitive evaluation, top-down modulation of attention and exteroceptive sensory processing, relevance detection and affective evaluation, as well as regions implicated in the representation of urges and in triggering autonomic processes. In contrast, physiosexual (i.e., physiological sexual) arousal is mediated by regions responsible for regulation and monitoring of initiated autonomic processes and emotions and for somatosensory processing. These circuits are interconnected by subcortical structures (putamen and claustrum) that provide exchange of sensorimotor information and crossmodal processing between and within the networks. Brain deactivations may imply attenuation of introspective processes and social cognition, but be necessary to release intrinsic inhibition of SA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.