ReviewJournal of mammary gland biology and neoplasia2013
The nipple: a simple intersection of mammary gland and integument, but focal point of organ function.
Review in Journal of mammary gland biology and neoplasia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 35 citations in OpenAlex.
- Reinnervation of Free Nipple Grafts Associated With Improved Erection Function.Plastic and reconstructive surgery. Global open · 2025Article
- A One-Stop Protocol to Assess Myocardial Fibrosis in Frozen and Paraffin Sections.Methods and protocols · 2022Article
- Size of supernumerary teats in sheep correlates with complexity of the anatomy and microenvironment.Journal of anatomy · 2020Article
- Thermal physiology of the lactating nipple influences the removal of human milk.Scientific reports · 2019Article
- Sinus-like dilatations of the mammary milk ducts, Ki67 expression, and CD3-positive T lymphocyte infiltration, in the mammary gland of wild European rabbits during pregnancy and lactation.Journal of anatomy · 2018Article
- Estrogen modulates mesenchyme-epidermis interactions in the adult nipple.Development (Cambridge, England) · 2017Article
- Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Linking suckling biomechanics to the development of the palate.Scientific reports · 2016Article
- Expansion of specialized epidermis induced by hormonal state and mechanical strain.Mechanisms of development · 2015Article
- Homozygous truncating PTPRF mutation causes athelia.Human genetics · 2014Article
- Evo-devo of the mammary gland.Journal of mammary gland biology and neoplasia · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Having glands that secrete milk to nourish neonatal offspring characterizes all mammals. We provide a brief overview of the development and anatomy of nipples and mammary glands in monotremes, marsupials, and marine mammals, and focus on the nipples and mammary glands in terrestrial eutherian species. We first classify eutherians into three groups: the altricial, precocial, and arboreal types based on their rearing system. We then summarize the physiology of lactation and the cell biology of nipples with specific focus on comparing these in the mouse, cow, and human, which represent the three different groups. Finally we propose that the nipple is an example of specialized epidermis. As specialized epidermis, it is dependent the underlying stroma for development and maintenance in adult life. The development of the nipple and signaling pathways that regulate its formation are described.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.