ArticleJournal of genetic counseling2014
Current Lynch syndrome tumor screening practices: a survey of genetic counselors.
Article in Journal of genetic counseling, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of the predictive effect of MSI status in colorectal cancer patients undergoing 5FU-based chemotherapy.BMC cancer · 2015Pooled it
- Creation of a Quality Payment Program Measure for Mismatch Repair or Microsatellite Instability Biomarker Testing Status in Colorectal, Endometrial, Gastroesophageal, or Small Bowel Carcinoma.Archives of pathology & laboratory medicine · 2024Article
- A simplified two-marker immunohistochemistry strategy for Lynch syndrome screening in endometrial cancer patients.Obstetrics & gynecology science · 2023Article
- Stakeholders' views of integrating universal tumour screening and genetic testing for colorectal and endometrial cancer into routine oncology.European journal of human genetics : EJHG · 2021Article
- From Genetics to Histomolecular Characterization: An Insight into Colorectal Carcinogenesis in Lynch Syndrome.International journal of molecular sciences · 2021Review
- Mismatch Repair Universal Screening of Endometrial Cancers (MUSE) in a Canadian Cohort.Current oncology (Toronto, Ont.) · 2021Article
- Effective Identification of Lynch Syndrome in Gastroenterology Practice.Current treatment options in gastroenterology · 2019Review
- Universal tumor screening for Lynch syndrome: perspectives of Canadian pathologists and genetic counselors.Journal of community genetics · 2019Article
- Universal tumor screening for Lynch syndrome: Perceptions of Canadian pathologists and genetic counselors of barriers and facilitators.Cancer medicine · 2019Article
- Decreasing Trends of Secondary Primary Colorectal Cancer among Women with Uterine Cancer: A Population-Based Analysis.Journal of clinical medicine · 2019Article
- Implementing universal Lynch syndrome screening (IMPULSS): protocol for a multi-site study to identify strategies to implement, adapt, and sustain genomic medicine programs in different organizational contexts.BMC health services research · 2018Article
- Using Somatic Mutations from Tumors to Classify Variants in Mismatch Repair Genes.American journal of human genetics · 2018Article
- Patient and provider perspectives on adherence to and care coordination of lynch syndrome surveillance recommendations: findings from qualitative interviews.Hereditary cancer in clinical practice · 2018Article
- Identifying "ownership" through role descriptions to support implementing universal colorectal cancer tumor screening for Lynch syndrome.Genetics in medicine : official journal of the American College of Medical Genetics · 2017Article
- A Systematic Review on the Existing Screening Pathways for Lynch Syndrome Identification.Frontiers in public health · 2017Article
- Care delivery considerations for widespread and equitable implementation of inherited cancer predisposition testing.Expert review of molecular diagnostics · 2017Review
- Qualitative Comparative Analysis: A Hybrid Method for Identifying Factors Associated with Program Effectiveness.Journal of mixed methods research · 2016Article
- Successful implementation of Lynch syndrome screening in a safety net institution.Journal of community genetics · 2016Article
- Stakeholder perspectives on implementing a universal Lynch syndrome screening program: a qualitative study of early barriers and facilitators.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Article
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An electronic survey of the National Society of Genetic Counselors Cancer Special Interest Group was conducted in July 2011 to assess Lynch syndrome tumor screening programs and identify barriers to implementation. Over half of respondents (52.8 %) reported having a routine Lynch syndrome tumor screening protocol for newly diagnosed colon and/or endometrial cancers, and approximately half of these used a universal approach. There was an increase in the number of those screening over time, especially in the past 3 years. Tumor screening methods varied; 34/53 (64.2 %) started with immunohistochemistry, 11/53 (20.8 %) started with microsatellite instability testing and 8/53 (15.1 %) performed both on newly diagnosed colorectal tumors. Just 21.7 % (23/106) of respondents indicated they have a tumor screening program in place for newly diagnosed endometrial cancers. Written consent is rarely obtained (7.1 %) and the method of how results were returned to the patient was variable among respondents. Prevalent barriers to implementation were concern about cost, bringing key players together and convincing medical staff of the necessity. Use of Lynch syndrome tumor screening is in clinical practice, but protocols vary widely. This survey provides a glimpse of current practices and common barriers, and identifies the need for tumor screening algorithms with outcomes data.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.