Evidence map›Paper›PMID 23674004›Full record

ArticleJournal of computer assisted tomography

Comparing primary tumors and metastatic nodes in head and neck cancer using intravoxel incoherent motion imaging: a preliminary experience.

Yonggang Lu, Jacobus F A Jansen, Hilda E Stambuk, Gaorav Gupta, Nancy Lee, Mithat Gonen, Andre Moreira, Yousef Mazaheri, Snehal G Patel, Joseph O Deasy and 2 more

Abstract readComparative Study
In one paragraph

Article in Journal of computer assisted tomography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Perfusion-driven Intravoxel Incoherent Motion (IVIM) MRI in Oncology: Applications, Challenges, and Future Trends.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2021
    Review
  7. Artificial Intelligence and Radiomics in Head and Neck Cancer Care: Opportunities, Mechanics, and Challenges.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2021
    Article
  8. Article
  9. Article
  10. Quantitative diffusion magnetic resonance imaging in head and neck tumors.Quantitative imaging in medicine and surgery · 2018
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Evaluation of Head and Neck Tumors with Functional MR Imaging.Magnetic resonance imaging clinics of North America · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yonggang LuDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Jacobus F A Jansen
Hilda E Stambuk
Gaorav Gupta
Nancy Lee
Mithat Gonen
Andre Moreira
Yousef Mazaheri
Snehal G Patel
Joseph O Deasy
Jatin P Shah
Amita Shukla-Dave

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
MR Dynamic Imaging and Spectroscopy in Head & Neck CancersR01CA115895 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DAVE, AMITA · 2006 to 2010
$1.6M
NCI NIH HHS 1 R01 CA115895NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA115895
6 · The paper itself

Abstract

objectiveThis study aimed to use intravoxel incoherent motion (IVIM) imaging for investigating differences between primary head and neck tumors and nodal metastases and to evaluate IVIM efficacy in predicting outcome.

methodsSixteen patients with head and neck cancer underwent IVIM diffusion-weighted imaging on a 1.5-T magnetic resonance imaging scanner. The significance of parametric difference between primary tumors and metastatic nodes were tested. Probabilities of progression-free survival and overall survival were estimated using the Kaplan-Meier method.

resultsIn comparison with metastatic nodes, the primary tumors had significantly higher vascular volume fraction (f) (P < 0.0009) and lower diffusion coefficient (D) (P < 0.0002). Patients with lower SD for D had prolonged progression-free survival and overall survival (P < 0.05).

conclusionsPretreatment IVIM measures were feasible in investigating the physiologic differences between the 2 tumor tissues. After appropriate validation, these findings might be useful in optimizing treatment planning and improving patient care.

Indexed as

AdultBiopsyData Interpretation, StatisticalDiffusion Magnetic Resonance ImagingEcho-Planar ImagingFemaleHead and Neck NeoplasmsHumansLymphatic MetastasisMaleMiddle AgedRetrospective StudiesSurvival Analysis

Identifiers

PMID23674004
PMCPMC3655331

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.