Evidence map›Paper›PMID 23673889›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2013

Efficacy of SISTA South Africa on sexual behavior and relationship control among isiXhosa women in South Africa: results of a randomized-controlled trial.

Gina M Wingood, Priscilla Reddy, Delia L Lang, Dorina Saleh-Onoya, Nikia Braxton, Sibusiso Sifunda, Ralph J DiClemente

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06022809 (Comparative Effectiveness of Individual Versus Group-level Interventions to Reduce HIV Risk Among African Immigrant Women), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06022809 nacompletednot on this mapstarted 2023, after this paper: background citation

Comparative Effectiveness of Individual Versus Group-level Interventions to Reduce HIV Risk Among African Immigrant Women

TypeinterventionalSponsorMassachusetts General HospitalRan2023 to 2026Enrolled149ConditionsHIV, Other STIsArmsDada Kwa Dada (individual-level), DADA (group-level)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  5. Investigating causes of the high prevalence of sexually transmitted infections in Du Noon.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gina M WingoodDepartment of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA 30342, USA. gwingoo@emory.edu
Priscilla Reddy
Delia L Lang
Dorina Saleh-Onoya
Nikia Braxton
Sibusiso Sifunda
Ralph J DiClemente

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
The CFAR Social & Behavioral Science Research Network National Scientific MeetingR13MH081733 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BLANK, MICHAEL B · 2008 to 2010
$223k
NIAID NIH HHS P30 AI050409NIMH NIH HHS R13 MH-081733-01A1PHS HHS NIAID/NIH P30 A1050409-06S1
6 · The paper itself

Abstract

backgroundThe HIV epidemic has a devastating impact among South African women. The current study evaluated the efficacy of SISTA South Africa, a culturally congruent HIV intervention for isiXhosa women in South Africa, which was adapted from SISTA, an HIV intervention for African American women.

methodsA randomized-controlled trial recruited 342 isiXhosa women aged 18-35 years. Participants were randomized to the general health comparison or the SISTA South Africa intervention. Xhosa-speaking peer health educators tailored the SISTA South Africa curriculum, while maintaining the core elements of the original SISTA intervention. Participants completed assessments at baseline and 6 months follow-up.

resultsRelative to participants in the comparison, participants in the HIV intervention reduced the frequency of unprotected vaginal intercourse acts (adjusted mean difference = 1.06; P = 0.02), were more likely to report not desiring dry sex (adjusted odds ratio = 0.229; 95% confidence interval = 0.10 to 0.47; P = 0.0001), and were more likely to perceive that their main sexual partner did not desire dry sex (adjusted odds ratio = 0.24; 95% confidence interval = 0.11 to 0.52; P = 0.0001). In addition, women randomized to the intervention also reported an increase in HIV knowledge, greater relationship control, and had more opposing attitudes toward HIV stigma. The HIV intervention did not reduce sexually transmitted infection incidence.

conclusionsThis trial demonstrates that an HIV intervention, which is adapted to enhance its gender and cultural relevance for rural isiXhosa women, can reduce self-reported sexual risk behaviors and enhance mediators of HIV among this vulnerable population.

Indexed as

Program EvaluationSexual BehaviorAdolescentAdultCondomsFemaleFollow-Up StudiesHealth Knowledge, Attitudes, PracticeHealth PromotionHIV InfectionsHumansMaleRisk-TakingRural PopulationSouth AfricaWomen's Health

Identifiers

PMID23673889
PMCPMC4130395

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.