Evidence map›Paper›PMID 23673881›Full record

ReviewJournal of acquired immune deficiency syndromes (1999)2013

Translation of biomedical prevention strategies for HIV: prospects and pitfalls.

Sten H Vermund, José A Tique, Holly M Cassell, Megan E Pask, Philip J Ciampa, Carolyn M Audet

Abstract readReview
In one paragraph

Review in Journal of acquired immune deficiency syndromes (1999), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Frequent HIV Testing: Impact on HIV Risk Among Chinese Men Who Have Sex with Men.Journal of acquired immune deficiency syndromes (1999) · 2016
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Human immunodeficiency virus vaccines.Infectious disease clinics of North America · 2014
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sten H VermundVanderbilt Institute for Global Health, Vanderbilt University School of Medicine, Nashville, TN, USA. sten.vermund@vanderbilt.edu
José A Tique
Holly M Cassell
Megan E Pask
Philip J Ciampa
Carolyn M Audet

Funding

The CFAR Social & Behavioral Science Research Network National Scientific MeetingR13HD074468 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI BLANK, MICHAEL B · 2012 to 2017
$385k
The CFAR Social & Behavioral Science Research Network National Scientific MeetingR13MH081733 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BLANK, MICHAEL B · 2008 to 2010
$223k
NICHD NIH HHS R13 HD074468NIMH NIH HHS R13 MH081733NIMH NIH HHS R13 MH-081733-01A1
6 · The paper itself

Abstract

Early achievements in biomedical approaches for HIV prevention included physical barriers (condoms), clean injection equipment (both for medical use and for injection drug users), blood and blood product safety, and prevention of mother-to-child transmission. In recent years, antiretroviral drugs to reduce the risk of transmission (when the infected person takes the medicines; treatment as prevention) or reduce the risk of acquisition (when the seronegative person takes them; preexposure prophylaxis) have proven to be efficacious. Circumcision of men has also been a major tool relevant for higher prevalence regions such as sub-Saharan Africa. Well-established prevention strategies in the control of sexually transmitted diseases and tuberculosis are highly relevant for HIV (ie, screening, linkage to care, early treatment, and contact tracing). Unfortunately, only slow progress is being made in some available HIV-prevention strategies such as family planning for HIV-infected women who do not want more children and prevention of mother-to-child HIV transmission. Current studies seek to integrate strategies into approaches that combine biomedical, behavioral, and structural methods to achieve prevention synergies. This review identifies the major biomedical approaches demonstrated to be efficacious that are now available. We also highlight the need for behavioral risk reduction and adherence as essential components of any biomedical approach.

Indexed as

HIVAIDS VaccinesAnti-Retroviral AgentsCircumcision, MaleFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalMaleNeedle-Exchange ProgramsPreventive Health ServicesAIDS VaccinesAnti-Retroviral Agents

Identifiers

PMID23673881
PMCPMC3725750

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.