Evidence map›Paper›PMID 23673790›Full record

ArticleAIDS and behavior2014

Could FDA approval of pre-exposure prophylaxis make a difference? A qualitative study of PrEP acceptability and FDA perceptions among men who have sex with men.

Kristen Underhill, Kathleen M Morrow, Don Operario, Kenneth H Mayer

Abstract read
In one paragraph

Article in AIDS and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kristen UnderhillYale Law School/Yale Center for Interdisciplinary Research on AIDS, Yale University, PO Box 208215, New Haven, CT, 06520, USA, kristen.underhill@yale.edu.
Kathleen M Morrow
Don Operario
Kenneth H Mayer

Funding

Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
PrEP for HIV Prevention in MSM: Mixed-Methods Study of Behavior & Message FramingK01MH093273 · NIMH · YALE UNIVERSITY · PI UNDERHILL, KRISTEN · 2011 to 2015
$873k
Advancing Reproductive Health: Qualitative Methods & Interdisciplinary MentorshipK24HD062645 · NICHD · MIRIAM HOSPITAL · PI GUTHRIE, KATE M · 2012 to 2016
$689k
NICHD NIH HHS K24 HD062645NIMH NIH HHS 5K01MH093273NIMH NIH HHS K01 MH093273NIMH NIH HHS P30 MH062294
6 · The paper itself

Abstract

The FDA has approved tenofovir-emtricitabine for use as HIV pre-exposure prophylaxis, but it is unknown how approval may affect PrEP acceptability among US men who have sex with men. We conducted 8 focus groups among 38 Rhode Island MSM, including 3 groups among 16 male sex workers and 5 groups among 22 men in the general MSM community. Participants reported wide-ranging beliefs regarding consequences and meanings of FDA approval. Some participants would not use PrEP without approval, while others perceived approval as irrelevant or less significant than other sources of information. Our results suggest that FDA approval sends a signal that directly shapes PrEP acceptability among some MSM, while indirect influences of approval may affect uptake by others. Efforts to educate MSM about PrEP can increase acceptability by incorporating information about FDA approval, and outreach strategies should consider how this information may factor into personal decisions about PrEP use.

Indexed as

Homosexuality, MalePatient Acceptance of Health CareAdenineAdultAnti-Retroviral AgentsChemopreventionDeoxycytidineEmtricitabineFocus GroupsHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansInterviews as TopicMaleOrganophosphonatesPerceptionAdenineAnti-Retroviral AgentsDeoxycytidineEmtricitabineOrganophosphonatesTenofovir

Identifiers

PMID23673790
PMCPMC3968829

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.