Evidence map›Paper›PMID 23673338›Full record

ReviewCurrent opinion in hematology2013

Progress against follicular lymphoma.

Jonathan H Schatz, Elisa Oricchio, Soham D Puvvada, H Guido Wendel

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in hematology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jonathan H SchatzDepartment of Medicine, University of Arizona, Tucson, Arizona, USA.
Elisa Oricchio
Soham D Puvvada
H Guido Wendel
Memorial Sloan Kettering Cancer Center · USUniversity of Arizona · US

Funding

The contribution of protein translation to tumorigenesisR01CA142798 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI WENDEL, HANS-GUIDO · 2010 to 2014
$1.9M
NCI NIH HHS R01 CA142798NCI NIH HHS R01-CA142798-01
6 · The paper itself

Abstract

purpose of reviewTo share the recent progress in research and new therapies against follicular lymphoma and highlight the exciting opportunities to improve the treatment of follicular lymphoma. RECENT

findingsFollicular lymphoma has been somewhat neglected by the research community, but recent genomic studies have identified key genetic lesions in follicular lymphoma. In addition, a new murine model is available to explore the function of these lesions in the development, progression, and treatment of follicular lymphoma. Moreover, new small-molecule inhibitors are now available that target key pathways in follicular lymphoma including B-cell receptor signaling and histone modifiers. SUMMARY: Follicular lymphoma is a very common and still incurable form of lymphoma. However, recent genomic and in-vivo biological studies are beginning to unveil the molecular drivers of follicular lymphoma. This coincides with the development of effective small-molecule inhibitors against key targets. Together these developments suggest that we are at a long overdue watershed moment in the treatment of follicular lymphoma.

Indexed as

AnimalsAntineoplastic AgentsDisease Models, AnimalHumansLymphoma, FollicularMiceProtein Kinase InhibitorsProto-Oncogene Proteins c-bcl-2Antineoplastic AgentsProtein Kinase InhibitorsProto-Oncogene Proteins c-bcl-2

Identifiers

PMID23673338
PMCPMC3881317
OpenAlexW1974287847

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.