Evidence map›Paper›PMID 23673327›Full record

ArticleDevelopmental cell2013

Scaling the MAPK signaling threshold during CNS patterning.

Charlotte Plestant, E S Anton

Abstract readComment
In one paragraph

Article in Developmental cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Associations ofNeuropsychiatric disease and treatment · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Charlotte PlestantNeuroscience Center and the Department of Cell Biology and Physiology, The University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
E S Anton

Funding

ROLE OF GGF IN RADIAL GLIAL CELL DEVELOPMENTR01MH060929 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ANTON, EVA S · 2000 to 2019
$5.7M
STOP SIGNALS FOR NEURONAL MIGRATION IN CEREBRAL CORTEXR01MH063660 · NIMH · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI ANTON, EVA S · 2000 to 2004
$936k
NIMH NIH HHS R01 MH060929NIMH NIH HHS R01 MH063660
6 · The paper itself

Abstract

Morphogenic gradients originating from signaling centers along the CNS developmental axes contribute to CNS patterning. Reporting in this issue of Developmental Cell, Lanctot et al. (2013) show that the Nde1-Lis1 complex interacts with Brap, a mitogen-activated protein kinase pathway negative regulator, to facilitate position-dependent modulation of neural progenitor fate and CNS patterning.

Identifiers

PMID23673327
PMCPMC3866018

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.