Evidence map›Paper›PMID 23673134›Full record

ArticleGenome medicine2013

Are randomized trials obsolete or more important than ever in the genomic era?

John Pa Ioannidis, Muin J Khoury

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Big data are coming to psychiatry: a general introduction.International journal of bipolar disorders · 2015
    Article
  7. Guidance for pharmacogenomic biomarker testing in labels of FDA-approved drugs.Genetics in medicine : official journal of the American College of Medical Genetics · 2015
    Article
  8. Evidence synthesis and guideline development in genomic medicine: current status and future prospects.Genetics in medicine : official journal of the American College of Medical Genetics · 2015
    Article
  9. Article
  10. Medicine. Big data meets public health.Science (New York, N.Y.) · 2014
    Article
  11. The ethics of clinical trials.Ecancermedicalscience · 2014
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John Pa IoannidisStanford Prevention Research Center, Department of Medicine and Department of Health Research and Policy, Stanford University School of Medicine, 1265 Welch Road, MSOB X306, Stanford, CA 94305, USA ; Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, CA 94305, USA.
Muin J KhouryOffice of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA ; Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, MD 20892, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID23673134
PMCPMC3707036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.