ArticleThe New phytologist2013
Nicotiana attenuata MPK4 suppresses a novel jasmonic acid (JA) signaling-independent defense pathway against the specialist insect Manduca sexta, but is not required for the resistance to the generalist Spodoptera littoralis.
Article in The New phytologist, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 57 citations in OpenAlex.
- Herbivore defense syndromes differ between native and invasive plant species.Plant diversity · 2026Article
- Functional Analysis of thePlants (Basel, Switzerland) · 2024Article
- Plant Kinases in the Perception and Signaling Networks Associated With Arthropod Herbivory.Frontiers in plant science · 2022Review
- Opposite roles of MAPKKK17 and MAPKKK21 againstFrontiers in plant science · 2022Article
- Potato StMPK7 is a downstream component of StMKK1 and promotes resistance to the oomycete pathogen Phytophthora infestans.Molecular plant pathology · 2021Article
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- Information theory tests critical predictions of plant defense theory for specialized metabolism.Science advances · 2020Article
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- Loliolide, a Carotenoid Metabolite, Is a Potential Endogenous Inducer of Herbivore Resistance.Plant physiology · 2019Article
- GhCPK33 Negatively Regulates Defense againstPlant physiology · 2018Article
- Plant Bio-Wars: Maize Protein Networks Reveal Tissue-Specific Defense Strategies in Response to a Root Herbivore.Journal of chemical ecology · 2018Article
- Arabidopsis response to the spider mite Tetranychus urticae depends on the regulation of reactive oxygen species homeostasis.Scientific reports · 2018Article
- Plant Perception and Short-Term Responses to Phytophagous Insects and Mites.International journal of molecular sciences · 2018Review
- ExpressingInternational journal of molecular sciences · 2018Article
- Argonaute 8 (AGO8) Mediates the Elicitation of Direct Defenses against Herbivory.Plant physiology · 2017Article
- MATI, a Novel Protein Involved in the Regulation of Herbivore-Associated Signaling Pathways.Frontiers in plant science · 2017Article
- Evolution of herbivore-induced early defense signaling was shaped by genome-wide duplications ineLife · 2016Article
- Why stay in a bad relationship? The effect of local host phenology on a generalist butterfly feeding on a low-ranked host.BMC evolutionary biology · 2016Article
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3 authors at 2 institutions in 1 country.
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Abstract
How plants tailor their defense responses to attack from different insects remains largely unknown. Here, we studied the role of a mitogen-activated protein kinase (MAPK), MPK4, in the resistance of a wild tobacco Nicotiana attenuata to two herbivores, the specialist Manduca sexta and the generalist Spodoptera littoralis. Stably transformed N. attenuata plants silenced in MPK4 (irMPK4) were generated and characterized for traits important for defense against herbivores. Only the oral secretions (OS) from M. sexta, but not the OS from S. littoralis or mechanical wounding, induced elevated levels of jasmonic acid (JA) in irMPK4 plants relative to the wild-type plants. Moreover, silencing of MPK4 strongly increased the resistance of N. attenuata to M. sexta in a fashion that was independent of COI1 (CORONATINE INSENSITIVE1)-mediated JA signaling. Untargeted metabolomic screening identified several new MPK4-dependent putative defensive compounds against M. sexta. By contrast, silencing of MPK4 did not affect the growth of the generalist insect S. littoralis, and we propose that this was because of the very low levels of fatty acid-amino acid conjugates (FACs) in S. littoralis OS. Thus, MPK4 is likely to be a key signaling element that enables plants to tailor defense responses to different attackers.
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