ArticleBMC medicine2013
Toward the future of psychiatric diagnosis: the seven pillars of RDoC.
Article in BMC medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02410954 (Transcranial Direct Current Stimulation), which is not on this map. Cited by 1,273 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transcranial Direct Current Stimulation (tDCS) as a Treatment for Acute Fear
Who cites it
1,273 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Common and disorder-specific aberrant activation during reward and loss processing in major depressive disorder and addiction: a meta-analysis of fMRI studies.Molecular psychiatry · 2026Pooled it
- Artificial Intelligence in Schizophrenia Spectrum Disorders: Current Use and Future Perspectives. A Systematic Mapping Literature Review.Alpha psychiatry · 2026Pooled it
- Common neural dysfunction in psychiatric disorders: Insights from a meta-analysis of resting-state fMRI studies.Translational psychiatry · 2025Pooled it
- Speech Emotion Recognition in Mental Health: Systematic Review of Voice-Based Applications.JMIR mental health · 2025Pooled it
- Neurofunctional representations of instrumental learning in psychosis: a meta-analysis of neuroimaging studies.Psychological medicine · 2025Pooled it
- The Effectiveness and Mechanisms of Action of App-Based Interventions for Improving Mental Health and Workplace Well-Being: Randomized Controlled Trial.JMIR mental health · 2026Trial
- Neural mechanisms underlying exposure and response prevention for obsessive compulsive disorder: A randomized controlled trial.Behaviour research and therapy · 2025Trial
- Distinct trajectories of perceived control over aversive stimulation predict affective reactions to stressors over and above objective control.Scientific reports · 2025Trial
- Cognitive neurodynamics of affective disorders.Cognitive neurodynamics · 2026Article
- Stress-induced adaptations in nucleus accumbens dopamine D1 receptor-expressing cells correspond to social avoidance behavior in male mice.IBRO neuroscience reports · 2026Article
- A hierarchical multi-scale framework for schizophrenia: integrating symptom networks, functional circuits, and molecular pathways.Molecular psychiatry · 2026Article
- Less systematic decision-making during delay discounting, but not discounting rate, is robustly linked to psychopathology.Journal of psychopathology and clinical science · 2026Article
- Emotional Responses (Intensity/Valence) Fulfill RDoC Criteria but Remain Excluded From Diagnostic Classifications of Mood Disorders.Bipolar disorders · 2026Review
- Associations of Mechanistically Partitioned Type 2 Diabetes Polygenic Risk With Psychiatric and Related Phenotypes in UK Biobank.Biological psychiatry global open science · 2026Article
- Alignment of natural language processing-derived RDoC scores with depression, anhedonia, and anxiety in psychiatric electronic health records.NPP - digital psychiatry and neuroscience · 2026Article
- Neurostimulation in the treatment of psychiatric disorders: Underlying mechanisms and critical analysis of circuit-based interventions.Molecular psychiatry · 2026Review
- Evaluating the Validity of Model Organisms: A Review and a New Framework for Biologists.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Review
- Exploring Psychopathology with Brain Fingerprinting Technique.Annals of neurosciences · 2026Article
- Schizophrenia, variability, and the Anna Karenina principle.Psychiatry research. Neuroimaging · 2026Article
- The cross-site reproducibility of MRI morphometric phenotypes in psychiatric disorders.Nature neuroscience · 2026Article
1,213 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent diagnostic systems for mental disorders rely upon presenting signs and symptoms, with the result that current definitions do not adequately reflect relevant neurobiological and behavioral systems--impeding not only research on etiology and pathophysiology but also the development of new treatments. DISCUSSION: The National Institute of Mental Health began the Research Domain Criteria (RDoC) project in 2009 to develop a research classification system for mental disorders based upon dimensions of neurobiology and observable behavior. RDoC supports research to explicate fundamental biobehavioral dimensions that cut across current heterogeneous disorder categories. We summarize the rationale, status and long-term goals of RDoC, outline challenges in developing a research classification system (such as construct validity and a suitable process for updating the framework) and discuss seven distinct differences in conception and emphasis from current psychiatric nosologies. SUMMARY: Future diagnostic systems cannot reflect ongoing advances in genetics, neuroscience and cognitive science until a literature organized around these disciplines is available to inform the revision efforts. The goal of the RDoC project is to provide a framework for research to transform the approach to the nosology of mental disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.