ArticleBMC genomics2013
Characterisation of a transcriptome to find sequence differences between two differentially migrating subspecies of the willow warbler Phylloscopus trochilus.
Article in BMC genomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 36 citations in OpenAlex.
- Common Chiffchaffs (Phylloscopus collybita) Diverge in a Genomic Region Associated With Migration Differences in Willow Warblers (Phylloscopus trochilus).Molecular ecology · 2026Article
- Parallel and convergent evolution in genes underlying seasonal migration.Evolution letters · 2025Article
- Genetic Control of Avian Migration: Insights from Studies in Latitudinal Passerine Migrants.Genes · 2023Review
- Inversions maintain differences between migratory phenotypes of a songbird.Nature communications · 2023Article
- The structure of songbird MHC class I reveals antigen binding that is flexible at the N-terminus and static at the C-terminus.Frontiers in immunology · 2023Article
- Clock-linked genes underlie seasonal migratory timing in a diurnal raptor.Proceedings. Biological sciences · 2022Article
- Sexual-biased gene expression of olfactory-related genes in the antennae of Conogethes pinicolalis (Lepidoptera: Crambidae).BMC genomics · 2020Article
- Length polymorphisms at two candidate genes explain variation of migratory behaviors in blackpoll warblers (Ecology and evolution · 2019Article
- Transcriptional Signatures in Liver Reveal Metabolic Adaptations to Seasons in Migratory Blackheaded Buntings.Frontiers in physiology · 2018Article
- Genetic differences between willow warbler migratory phenotypes are few and cluster in large haplotype blocks.Evolution letters · 2017Article
- Patterns of genetic, phenotypic, and acoustic variation across a chiffchaff (Ecology and evolution · 2017Article
- Antennal transcriptome and differential expression of olfactory genes in the yellow peach moth, Conogethes punctiferalis (Lepidoptera: Crambidae).Scientific reports · 2016Article
- Gene expression in the brain of a migratory songbird during breeding and migration.Movement ecology · 2016Article
- Characterization of early transcriptional responses to cadmium in the root and leaf of Cd-resistant Salix matsudana Koidz.BMC genomics · 2015Article
- No evidence for assortative mating within a willow warbler migratory divide.Frontiers in zoology · 2014Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnimal migration requires adaptations in morphological, physiological and behavioural traits. Several of these traits have been shown to possess a strong heritable component in birds, but little is known about their genetic architecture. Here we used 454 sequencing of brain-derived transcriptomes from two differentially migrating subspecies of the willow warbler Phylloscopus trochilus to detect genes potentially underlying traits associated with migration.
resultsThe transcriptome sequencing resulted in 1.8 million reads following filtering steps. Most of the reads (84%) were successfully mapped to the genome of the zebra finch Taeniopygia gutatta. The mapped reads were situated within at least 12,101 predicted zebra finch genes, with the greatest sequencing depth in exons. Reads that were mapped to intergenic regions were generally located close to predicted genes and possibly located in uncharacterized untranslated regions (UTRs). Out of 85,000 single nucleotide polymorphisms (SNPs) with a minimum sequencing depth of eight reads from each of two subspecies-specific pools, only 55 showed high differentiation, confirming previous studies showing that most of the genetic variation is shared between the subspecies. Validation of a subset of the most highly differentiated SNPs using Sanger sequencing demonstrated that several of them also were differentiated between an independent set of individuals of each subspecies. These SNPs were clustered in two chromosome regions that are likely to be influenced by divergent selection between the subspecies and that could potentially be associated with adaptations to their different migratory strategies.
conclusionsOur study represents the first large-scale sequencing analysis aiming at detecting genes underlying migratory phenotypes in birds and provides new candidates for genes potentially involved in migration.
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