Evidence map›Paper›PMID 23672453›Full record

ReviewInternational journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group2013

Simulation techniques in hyperthermia treatment planning.

Margarethus M Paulides, Paul R Stauffer, Esra Neufeld, Paolo F Maccarini, Adamos Kyriakou, Richard A M Canters, Chris J Diederich, Jurriaan F Bakker, Gerard C Van Rhoon

Abstract readReview
In one paragraph

Review in International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Automatic specific absorption rate (SAR) prediction for hyperthermia treatment planning using deep learning method.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Spatio-Spectral Ultrasound Characterization of Reflection and Transmission Through Bone With Temperature Dependence.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Whither Magnetic Hyperthermia? A Tentative Roadmap.Materials (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Margarethus M PaulidesHyperthermia Unit, Department of Radiation Oncology, Daniel den Hoed Cancer Centre, Erasmus Medical Centre, Rotterdam, The Netherlands. m.paulides@erasmusmc.nl
Paul R Stauffer
Esra Neufeld
Paolo F Maccarini
Adamos Kyriakou
Richard A M Canters
Chris J Diederich
Jurriaan F Bakker
Gerard C Van Rhoon

Funding

TISSUEP01CA042745 · NCI · DUKE UNIVERSITY · PI JONES, ELLEN L · 1987 to 2009
$28.6M
Radiometry Controlled Conformal Array Heat ApplicatorR01CA070761 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STAUFFER, PAUL RATH · 1996 to 2006
$895k
Miniature Deep Thermal Imager for Continuous Monitoring of BAT MetabolismR21DK092912 · NIDDK · DUKE UNIVERSITY · PI MACCARINI, PAOLO FRANCESCO, STAUFFER, PAUL RATH · 2011 to 2012
$416k
NCI NIH HHS P01 CA042745NCI NIH HHS P01-CA42745NCI NIH HHS R01 CA070761NIDDK NIH HHS R21 DK092912
6 · The paper itself

Abstract

Abstract Clinical trials have shown that hyperthermia (HT), i.e. an increase of tissue temperature to 39-44 °C, significantly enhance radiotherapy and chemotherapy effectiveness [1]. Driven by the developments in computational techniques and computing power, personalised hyperthermia treatment planning (HTP) has matured and has become a powerful tool for optimising treatment quality. Electromagnetic, ultrasound, and thermal simulations using realistic clinical set-ups are now being performed to achieve patient-specific treatment optimisation. In addition, extensive studies aimed to properly implement novel HT tools and techniques, and to assess the quality of HT, are becoming more common. In this paper, we review the simulation tools and techniques developed for clinical hyperthermia, and evaluate their current status on the path from 'model' to 'clinic'. In addition, we illustrate the major techniques employed for validation and optimisation. HTP has become an essential tool for improvement, control, and assessment of HT treatment quality. As such, it plays a pivotal role in the quest to establish HT as an efficacious addition to multi-modality treatment of cancer.

Indexed as

Hyperthermia, InducedModels, BiologicalComputer SimulationHumansNeoplasms

Identifiers

PMID23672453
PMCPMC3711016

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.