SynthesisHPB : the official journal of the International Hepato Pancreato Biliary Association2014
Laparoscopic versus open liver resection: a meta-analysis of long-term outcome.
Synthesis in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 8 syntheses or guidelines pooled it, 123 citations in OpenAlex.
- Pooled it
- Survival Benefit of Surgical Treatment Added Into Systemic Treatment for Isolated Breast Cancer Liver Metastases: A Systematic Review and Meta-Analysis.Frontiers in surgery · 2021Pooled it
- Outcomes of laparoscopic repeat liver resection for recurrent liver cancer: A system review and meta-analysis.Medicine · 2019Pooled it
- Open versus laparoscopic hepatic resection for hepatocellular carcinoma: a systematic review and meta-analysis.Surgical endoscopy · 2019Pooled it
- Meta-analysis of short- and long-term outcomes after pure laparoscopic versus open liver surgery in hepatocellular carcinoma patients.Surgical endoscopy · 2019Pooled it
- Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma.Updates in surgery · 2017Pooled it
- Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations.World journal of surgery · 2016Pooled it
- Management of hepatocellular carcinoma: an overview of major findings from meta-analyses.Oncotarget · 2016Pooled it
- Laparoscopic versus open partial hepatectomy for hepatocellular carcinoma in F4 cirrhosis: A propensity score-matched study of perioperative safety.Annals of hepato-biliary-pancreatic surgery · 2026Article
- Effects of Sugammadex on the Coagulation Profile of Living Liver Donors Undergoing Hepatectomy: A Case-Control Study.Medicina (Kaunas, Lithuania) · 2025Article
- Laparoscopic liver resection versus radiofrequency ablation for caudate lobe solitary hepatocellular carcinoma: A propensity score matching study.Cancer medicine · 2024Article
- Practice variation and outcomes of minimally invasive minor liver resections in patients with colorectal liver metastases: a population-based study.Surgical endoscopy · 2023Article
- Outcomes and Patient Selection in Laparoscopic vs. Open Liver Resection for HCC and Colorectal Cancer Liver Metastasis.Cancers · 2023Review
- Laparoscopic and Robot-Assisted Hepatic Surgery: An Historical Review.Journal of clinical medicine · 2022Review
- Multivisceral Resection in Robotic Liver Surgery.Cancers · 2022Review
- Operative Time, Age, and Serum Albumin Predict Surgical Morbidity After Laparoscopic Liver Surgery.Surgical innovation · 2021Article
- Laparoscopic versus open hepatectomy for hepatocellular carcinoma with cirrhosis: a single-center propensity score matching analysis.Annals of translational medicine · 2021Article
- Recent update on comprehensive therapy for advanced hepatocellular carcinoma.World journal of gastrointestinal oncology · 2021Review
- A propensity-matched study of full laparoscopic versus hand-assisted minimal-invasive liver surgery.Surgical endoscopy · 2021Article
- Laparoscopic hepatectomy versus open hepatectomy for hepatocellular carcinoma: A propensity case-matched analysis of the long-term survival.Annals of hepato-biliary-pancreatic surgery · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic liver resection is growing in popularity, but the long-term outcome of patients undergoing laparoscopic liver resection for malignancy has not been established. This paper is a meta-analysis and compares the long-term survival of patients undergoing laparoscopic (LHep) versus open (OHep) liver resection for the treatment of malignant liver tumours.
methodsA PubMed database search identified comparative human studies analysing LHep versus OHep for malignant tumours. Clinical and survival parameters were extracted. The search was last conducted on 18 March 2012.
resultsIn total, 1002 patients in 15 studies were included (446 LHep and 556 OHep). A meta-analysis of overall survival showed no difference [1-year: odds ratio (OR) 0.71, 95% confidence interval (CI) 0.42 to 1.20, P = 0.202; 3-years: OR 0.76, 95% CI 0.56 to 1.03, P = 0.076; 5-years: OR 0.8, 95% CI 0.59 to 1.10, P = 0.173]. Subset analyses of hepatocellular carcinoma (HCC) and colorectal metastases (CRM) were performed. There was no difference in the 1-, 3-, and 5-year survival for HCC or in the 1-year survival for CRM, however, a survival advantage was found for CRM at 3 years (LHep 80% versus OHep 67.4%, P = 0.036).
conclusionsLaparoscopic surgery should be considered an acceptable alternative for the treatment of malignant liver tumours.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.