ArticleJournal of diabetes research2013
Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension.
Article in Journal of diabetes research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
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- Is the Association Between Sports Participation in Childhood and Adolescence and Cardiometabolic Risk Mediated by Cardiorespiratory Fitness in Adulthood?American journal of human biology : the official journal of the Human Biology Council · 2025Observational
- Phytochemical Screening and Antidiabetic Efficacy ofACS omega · 2024Article
- Postloading insulinemia is independently associated with arterial stiffness in young Japanese persons.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Role of dyslipidemia in early vascular aging syndromeTurkish journal of medical sciences · 2021Article
- Comparison of Hemoglobin Alc, Glycated Albumin and Fasting Plasma Glucose for Prediction of Arterial Stiffness in Chinese Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- High triglyceride to high-density lipoprotein cholesterol ratio and arterial stiffness in postmenopausal Korean women.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Association between Sports Participation in Early Life and Arterial Intima-Media Thickness among Adults.Medicina (Kaunas, Lithuania) · 2018Article
- Lipoprotein ratios are better than conventional lipid parameters in predicting arterial stiffness in young men.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Triglyceride to HDL-C ratio and increased arterial stiffness in apparently healthy individuals.International journal of clinical and experimental medicine · 2015Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim. We investigated the relationship between brachial-ankle pulse wave velocity (baPWV) and glucose levels, insulin sensitivity, and beta-cell function in Chinese individuals with or without hypertension. Methods. We recruited 3137 nondiabetic individuals whose age, body mass index (BMI), glucose levels, blood pressure (BP), lipids, hemoglobin A1C (HbA1c), baPWV, and insulin levels were measured. Results. In normotensive group, 2 h glucose levels (β = 0.046, P < 0.001) associated with baPWV, showed a significant increase in patients with NG as compared to those with DM (P = 0.032). The hypertensive group showed no such differences. The Matsuda index (β = 0.114, P < 0.001) and HOMA- β (β = 0.045, P < 0.001) were negatively correlated with baPWV while lnHOMA-IR (β = 0.196, P = 0.076) and the Quantitative Insulin Sensitivity Check Index (QUICKI) (β = 0.226, P = 0.046) showed a borderline negative correlation. BaPWV significantly decreased (P = 0.032) with an increase in insulin sensitivity in individuals with both normal BP and glucose tolerance. Conclusions. BaPWV was significantly associated with 2 h glucose levels, insulin sensitivity and beta-cell function in normotensive population, whereas in hypertensive individuals, BP was the dominant factor influencing arterial stiffness. Individuals with abnormal insulin sensitivity in the absence of diabetes and hypertension are also at an increased risk of arterial stiffness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.