ArticlePloS one2013
Smoking and risk of kidney failure in the Singapore Chinese health study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Modifiable Lifestyle Factors for Primary Prevention of CKD: A Systematic Review and Meta-Analysis.Journal of the American Society of Nephrology : JASN · 2021Pooled it
- Effects of Flammable and Non-Flammable Nicotine Products on Kidney Health.Medical sciences (Basel, Switzerland) · 2026Review
- Association of Smoking with Chronic Kidney Disease Stages 3 to 5: A Mendelian Randomization Study.Health data science · 2024Article
- Estimation of the Cadmium Nephrotoxicity Threshold from Loss of Glomerular Filtration Rate and Albuminuria.Toxics · 2023Article
- Cadmium-Induced Tubular Dysfunction in Type 2 Diabetes: A Population-Based Cross-Sectional Study.Toxics · 2023Article
- Secondhand smoke, genetic susceptibility, and incident chronic kidney disease in never smokers: A prospective study of a selected population from the UK Biobank.Tobacco induced diseases · 2023Article
- Predictors of rapid progression of estimated glomerular filtration rate among persons living with diabetes and/or hypertension in Ghana: Findings from a multicentre study.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Impact of Hospitalization on the Quality of Life of Patients with Chronic Kidney Disease in Saudi Arabia.International journal of environmental research and public health · 2022Article
- Lifestyle behaviors associated with the initiation of renal replacement therapy in Japanese patients with chronic kidney disease: a retrospective cohort study using a claims database linked with specific health checkup results.Environmental health and preventive medicine · 2021Article
- Healthful dietary patterns and risk of end-stage kidney disease: the Singapore Chinese Health Study.The American journal of clinical nutrition · 2021Article
- Gender-biased kidney damage in mice following exposure to tobacco cigarette smoke: More protection in premenopausal females.Physiological reports · 2020Article
- Association of smoking with incident CKD risk in the general population: A community-based cohort study.PloS one · 2020Article
- Smoking and risk of incident end-stage kidney disease in general population: A Nationwide Population-based Cohort Study from Korea.Scientific reports · 2019Article
- Pulse Pressure and the Risk of End-Stage Renal Disease Among Chinese Adults in Singapore: The Singapore Chinese Health Study.Journal of the American Heart Association · 2019Article
- Sleep duration and risk of end-stage renal disease: the Singapore Chinese Health Study.Sleep medicine · 2019Article
- Long-term incense use and the risk of end-stage renal disease among Chinese in Singapore: the Singapore Chinese health study.BMC nephrology · 2019Article
- Smoking patterns and chronic kidney disease in US Hispanics: Hispanic Community Health Study/Study of Latinos.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2016Article
- Physical activity and risk of end-stage kidney disease in the Singapore Chinese Health Study.Nephrology (Carlton, Vic.) · 2015Article
- Experiences of adult smokers from the concepts of smoking: A content analysis.Iranian journal of nursing and midwifery research · 2014Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThe relationship between smoking and risk of kidney failure, especially in people of Chinese origin, is not clear. We analyzed data from the Singapore Chinese Health Study to investigate whether smoking increases the risk of kidney failure.
methodsThe Singapore Chinese Health Study is a population-based cohort of 63,257 Chinese adults enrolled between 1993 and 1998. Information on smoking status was collected at baseline. Incidence of kidney failure was identified via record linkage with the nationwide Singapore Renal Registry until 2008. Kidney failure was defined by one of the following: 1) serum creatinine level of more than or equal to 500 µmol/l (5.7 mg/dl), 2) estimated glomerular filtration rate of less than 15 ml/min/1.73 m(2), 3) undergoing hemodialysis or peritoneal dialysis, 4) undergone kidney transplantation. Cox proportional hazard regression analysis was performed for the outcome of kidney failure after adjusting for age, education, dialect, herbal medications, body mass index, sex, physician-diagnosed hypertension and diabetes mellitus.
resultsThe mean age of subjects was 55.6 years at baseline, and 44% were men. Overall 30.6% were ever smokers (current or former) at baseline. A total of 674 incident cases of kidney failure occurred during a median follow-up of 13.3 years. Among men, smokers had a significant increase in the adjusted risk of kidney failure [hazard ratio (HR): 1.29; 95% CI: 1.02-1.64] compared to never smokers. There was a strong dose-dependent association between number of years of smoking and kidney failure, (p for trend = 0.011). The risk decreased with prolonged cessation (quitting ≥10 years since baseline). The number of women smokers was too few for conclusive relationship. LIMITATION: Information on baseline kidney function was not available.
conclusionsCigarette smoking is associated with increased risk of kidney failure among Chinese men. The risk appears to be dose- and duration-dependent and modifiable after long duration of cessation.
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