Evidence map›Paper›PMID 23671440›Full record

ArticleArchives of medical science : AMS2013

The role of counselling and other factors in compliance of postmenopausal osteoporotic patients to alendronate 70 therapy.

Ewa Sewerynek, Hanna Horst-Sikorska, Wioletta Stępień-Kłos, Agnieszka Antkowiak, Małgorzata Janik, Karol Cieślak, Michalina Marcinkowska, Agnieszka Cegłowska, Michał Stuss

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Improving drug adherence in osteoporosis: an update on more recent studies.Therapeutic advances in musculoskeletal disease · 2018
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Long-term persistence with anti-osteoporosis drugs after fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ewa SewerynekDepartment of Endocrine Disorders and Bone Metabolism, Medical University of Lodz, Poland ; Outpatient Clinic of Osteoporosis, Lodz, Poland.
Hanna Horst-Sikorska
Wioletta Stępień-Kłos
Agnieszka Antkowiak
Małgorzata Janik
Karol Cieślak
Michalina Marcinkowska
Agnieszka Cegłowska
Michał Stuss

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the study was to assess the role of patient counselling, nurse assistance and effects of biochemical examinations in adherence of women with postmenopausal osteoporosis to alendronate 70 administration over 12 months of therapy. MATERIAL AND

methodsCompliance and persistence to alendronate 70 therapy were assessed in a prospective study of 123 postmenopausal women, followed up for one year. The patients were divided into 4 groups (controls, counselled group, biochemical group and nurse assisted group) with monitoring every 6 months; in the nurse assisted group, additional phone contacts were made after 3 and 9 months of treatment. After 12 months, compliance and persistence were analysed. The medication possession ratio (MPR) was regarded as optimal when its value exceeded 80%.

resultsThe compliance to alendronate 70 therapy was 54.03% in the control group and the mean persistence with medication was 197 days. The MPR above 80% was observed in 37.5%, and, after 1 year, 43.75% of patients were found persistent with the therapy. In the remaining groups, both compliance and persistence were higher but not statistically significantly, compared to the control group. Neither patient's age, education, diet, nor physical activity influenced the compliance with prescribed therapy. The most common reason to discontinue therapy was either its side effects or smoking.

conclusionsThe obtained results suggest that better adherence with medical recommendations is observed in patients who receive additional attention, e.g. counselling, biochemical tests or nursing care. The critical elements for therapy discontinuation were side effects and smoking.

Indexed as

adherencealendronatepersistencereasons for therapy discontinuation

Identifiers

PMID23671440
PMCPMC3648838

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.