ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2013
Vocal training mitigates age-related changes within the vocal mechanism in old rats.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 49 citations in OpenAlex.
- High-Speed Characterization of Vocal Fold Vibrations in Normally Cycling and Postmenopausal Women: Randomized Double-Blind Analyses.Journal of speech, language, and hearing research : JSLHR · 2021Trial
- Behavioral characterization of bulbar sensorimotor function in a rat model of Alexander disease.Behavioural brain research · 2026Article
- The evidence for old age motor neuron death: A scoping review.Physiological reports · 2026Article
- The role of ultrasonic vocalizations in rat laryngological investigations.Physiology & behavior · 2025Review
- Rats that learn to vocalize for food reward emit longer and louder appetitive calls and fewer short aversive calls.PloS one · 2024Review
- Positron emission tomography neuroimaging of [Frontiers in neuroscience · 2024Article
- Utilizing novel recurrent laryngeal motor nerve conduction studies to characterize the aging larynx: A pilot study.Laryngoscope investigative otolaryngology · 2023Article
- Changes in ultrasonic vocalizations after unilateral cerebral ischemia in a rat stroke model.Behavioural brain research · 2023Article
- Effects of social isolation on 50-kHz ultrasonic vocalizations, affective state, cognition, and neurotransmitter concentrations in the ventral tegmental and locus coeruleus of adult rats.Behavioural brain research · 2023Article
- Early ultrasonic vocalization deficits and related thyroarytenoid muscle pathology in the transgenic TgF344-AD rat model of Alzheimer's disease.Frontiers in behavioral neuroscience · 2023Article
- Metabolomic Expression of Laryngeal and Hindlimb Muscles in Adult versus Senescent Rats.The Annals of otology, rhinology, and laryngology · 2022Article
- Semi-Automated Training of Rat Ultrasonic Vocalizations.Frontiers in behavioral neuroscience · 2022Article
- Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease.Behavioural brain research · 2021Article
- Rat Models of Vocal Deficits in Parkinson's Disease.Brain sciences · 2021Review
- Exercise Science and the Vocalist.Journal of voice : official journal of the Voice Foundation · 2021Article
- The Effects of Menopause on Neuromuscular Parameters of the Rat Vocal Folds.The Laryngoscope · 2021Article
- Exercise Science and the Vocalist.Journal of voice : official journal of the Voice Foundation · 2021Review
- Biological and Acoustic Sex Differences in Rat Ultrasonic Vocalization.Brain sciences · 2021Review
- Effects of Vocal Training on Thyroarytenoid Muscle Neuromuscular Junctions and Myofibers in Young and Older Rats.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- Preparation of the Rat Vocal Fold for Neuromuscular Analyses.Journal of visualized experiments : JoVE · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Aging affects voice production and is associated with reduced communicative ability and quality of life. Voice therapy is a critical component of treatment, but its effects on neuromuscular mechanisms are unknown. The ultrasonic vocalizations (USVs) of rats can be used to test the effects of aging and voice use on the laryngeal neuromuscular system. This study tested the hypothesis that age-related changes in the USVs of rats and laryngeal neuromuscular junctions can be reversed through vocal exercise. Young and old rats were trained for 8 weeks to increase their USVs and were compared with a no intervention group pre- and post-treatment. USV acoustics and aspects of neuromuscular junction (NMJ) morphology were measured in the thyroarytenoid muscle. Vocal training reduced or eliminated some age differences found in both USVs and NMJs. We conclude that vocal exercise may assist in mitigating age-related changes in voice characteristics and underlying neuromuscular adaptations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.