Evidence map›Paper›PMID 23671010›Full record

ReviewJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2013

Forum on bone and skeletal muscle interactions: summary of the proceedings of an ASBMR workshop.

Lynda F Bonewald, Douglas P Kiel, Thomas L Clemens, Karyn Esser, Eric S Orwoll, Regis J O'Keefe, Roger A Fielding

Abstract readReview
In one paragraph

Review in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 118 citations in OpenAlex.

  1. Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
    Trial
  2. Review
  3. Pharmacologic Mechanisms ofFood science & nutrition · 2025
    Review
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Lynda F BonewaldDepartment of Oral and Craniofacial Science, School of Dentistry, University of Missouri-Kansas City, Kansas City, MO 64108, USA. Bonewaldl@umkc.edu
Douglas P Kiel
Thomas L Clemens
Karyn Esser
Eric S Orwoll
Regis J O'Keefe
Roger A Fielding
Harvard University · USJean Mayer Human Nutrition Research Center on Aging · USJohns Hopkins University · USOregon Health & Science University · USUniversity of Kentucky · USUniversity of Missouri–Kansas City · USUniversity of Rochester Medical Center · US

Funding

Translating PTH Therapy as an Adjuvant for Structural AllograftingP50AR054041 · NIAMS · UNIVERSITY OF ROCHESTER · PI SCHWARZ, EDWARD M. · 2006 to 2016
$15.7M
The Growth Hormone/IGF-1 Axis in Skeletal MuscleR01AR057868 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI CLEMENS, THOMAS L · 2010 to 2014
$1.8M
BetaCatenin Regulation of Skeletal Muscle HypertrophyR01AR061939 · NIAMS · UNIVERSITY OF KENTUCKY · PI ESSER, KARYN A, MCCARTHY, JOHN JOSEPH · 2012 to 2016
$1.7M
Muscle-Bone Endocrine AxisRC2AR058962 · NIAMS · UNIVERSITY OF MISSOURI KANSAS CITY · PI BONEWALD, LYNDA F, BROTTO, MARCO · 2009 to 2010
$1.1M
ASBMR Topical Meeting on Bone and Skeletal Muscle InteractionsR13AR063602 · NIAMS · AMERICAN SOCIETY FOR BONE & MINERAL RES · PI BONEWALD, LYNDA F · 2012 to 2012
$130k
NIAMS NIH HHS P50 AR054041NIAMS NIH HHS R01 AR057868NIAMS NIH HHS R01 AR061939NIAMS NIH HHS R13 AR063602NIAMS NIH HHS R13AR063602NIAMS NIH HHS RC2 AR058962
6 · The paper itself

Abstract

Annual costs are enormous for musculoskeletal diseases such as osteoporosis and sarcopenia and for bone and muscle injuries, costing billions annually in health care. Although it is clear that muscle and bone development, growth, and function are connected, and that muscle loads bone, little is known regarding cellular and molecular interactions between these two tissues. A conference supported by the National Institutes of Health (NIH) and the American Society for Bone and Mineral Research (ASBMR) was held in July 2012 to address the enormous burden of musculoskeletal disease. National and international experts in either bone or muscle presented their findings and their novel hypotheses regarding muscle-bone interactions to stimulate the exchange of ideas between these two fields. The immediate goal of the conference was to identify critical research themes that would lead to collaborative research interactions and grant applications focusing on interactions between muscle and bone. The ultimate goal of the meeting was to generate a better understanding of how these two tissues integrate and crosstalk in both health and disease to stimulate new therapeutic strategies to enhance and maintain musculoskeletal health.

Indexed as

Congresses as TopicAgingBone and BonesHumansMechanotransduction, CellularMuscle DevelopmentMuscle, SkeletalOsteogenesisAGINGBONEMUSCLEMUSCULOSKELETALOSTEOPOROSISSARCOPENIA

Identifiers

PMID23671010
PMCPMC3749267
OpenAlexW1664142100

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.