Evidence map›Paper›PMID 23671003›Full record

ArticleChembiochem : a European journal of chemical biology2013

Pulse radiolysis studies on the reaction of the reduced vitamin B₁₂ complex Cob(II)alamin with superoxide.

Rohan S Dassanayake, Diane E Cabelli, Nicola E Brasch

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Insights on Localized and Systemic Delivery of Redox-Based Therapeutics.Oxidative medicine and cellular longevity · 2018
    Review
  3. Comparative studies of reaction of cobalamin (II) and cobinamide (II) with sulfur dioxide.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rohan S DassanayakeDepartment of Chemistry & Biochemistry and School of Biomedical Sciences, Kent State University, Kent, OH 44242, USA.
Diane E Cabelli
Nicola E Brasch
Brookhaven National Laboratory · USKent State University · US

Funding

Scavenging of Reactive Oxygen and Nitrogen Species by CobalaminsR15GM094707 · NIGMS · KENT STATE UNIVERSITY · PI BRASCH, NICOLA ELIZABETH · 2011 to 2011
$219k
NIGMS NIH HHS 1R15GM094707-01A1NIGMS NIH HHS R15 GM094707
6 · The paper itself

Abstract

O₂.- scavenger: The rate constant for the rapid reaction of the ROS superoxide with the reduced vitamin B₁₂ radical complex cob(II)alamin was directly determined to be 3.8×10(8) M⁻¹ s⁻¹. This rate was independent of pH over the range 5.5-8.7. These results have implications for studying the use of B₁₂ supplements to combat diseases associated with oxidative stress.

Indexed as

Hydrogen-Ion ConcentrationKineticsOxidation-ReductionSuperoxidesVitamin B 12cob(II)alaminSuperoxidesVitamin B 12

Identifiers

PMID23671003
PMCPMC3737425
OpenAlexW2094077348

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.