Evidence map›Paper›PMID 23670991›Full record

ArticleObesity (Silver Spring, Md.)2013

Advantages of percent weight loss as a method of reporting weight loss after Roux-en-Y gastric bypass.

Ida J Hatoum, Lee M Kaplan

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  6. Rising in level of liver biomarkers after different types of bariatric surgery; is there any concern?Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2026
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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ida J HatoumObesity, Metabolism & Nutrition Institute and Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
Lee M Kaplan

Funding

Small Animal Metabolic Surgery (SAMS) Resource CoreRC2DK088661 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KAPLAN, LEE MICHAEL · 2009 to 2010
$6.1M
Neuroendocrine Response to Gastric Bypass in Nonhuman PrimatesRC4DK090956 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI ELMQUIST, JOEL K., GROVE, KEVIN L · 2010 to 2010
$3.8M
Genetic and Clinical Predictors of Weight Loss after Roux-en-Y Gastric BypassF32DK093257 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI HATOUM, IDA JODETTE · 2011 to 2013
$170k
NIDDK NIH HHS DK088661NIDDK NIH HHS DK090956NIDDK NIH HHS DK093257NIDDK NIH HHS F32 DK093257NIDDK NIH HHS RC2 DK088661NIDDK NIH HHS RC4 DK090956
6 · The paper itself

Abstract

objectiveAlthough Roux-en-Y gastric bypass (RYGB) is an effective treatment for severe obesity, weight loss (WL) after this operation is highly variable. Accurate predictors of outcome would thus be useful in identifying those patients who would most benefit from this invasive therapy. WL has been characterized using several different metrics, including the number of BMI units lost (ΔBMI), percent baseline WL (%WL), and percent excess body WL (%EBWL). To identify clinically relevant predictors most sensitively, it is necessary to avoid confounding by other factors, including preoperative BMI (pBMI), the strongest known predictor of RYGB-induced WL. DESIGN AND

methodsTo determine the WL measure least associated with pBMI, outcomes of 846 patients undergoing RYGB were analyzed.

resultsPatients in this cohort had an average pBMI of 50.0 kg/m(2) at baseline. At weight nadir, they lost an average 19.4 kg/m(2), 38.7% WL, and 81.2% EBWL. pBMI was strongly and positively associated with ΔBMI at both 1 year (r = 0.56, P = 4.7 × 10(-51)) and nadir (r = 0.58, P = 2.8 × 10(-77)) and strongly but negatively associated with %EBWL at 1 year (r = -0.52, P = 3.8 × 10(-44)) and nadir (r = -0.45, P = 7.2×10(-43)). In contrast, pBMI was not significantly associated with %WL at 1 year (r = 0.04, P = 0.33) and only weakly associated at nadir (r = 0.13, P = 0.0002).

conclusionsOf the metrics examined, %WL is the parameter describing WL after RYGB least influenced by pBMI. It thus improves comparison of WL outcomes across studies of patients undergoing surgery and facilitates the most sensitive identification of novel predictors of surgery-induced WL. We therefore is recommend that %WL be adopted more broadly in reporting weight loss after RYGB.

Indexed as

Anastomosis, Roux-en-YWeight LossAdultBody Mass IndexCohort StudiesEndpoint DeterminationFemaleHumansLinear ModelsMaleMiddle AgedObesity, MorbidPostoperative PeriodPreoperative PeriodTreatment Outcome

Identifiers

PMID23670991
PMCPMC3744630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.