Evidence map›Paper›PMID 23670332›Full record

ReviewBrazilian journal of otorhinolaryngology

Head and neck cancer: causes, prevention and treatment.

Ana Lívia Silva Galbiatti, João Armando Padovani-Junior, José Victor Maníglia, Cléa Dometilde Soares Rodrigues, Érika Cristina Pavarino, Eny Maria Goloni-Bertollo

Abstract readReview
In one paragraph

Review in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Cyclooxygenase-2-1195G>A Polymorphism and Head and Neck Squamous Cell Carcinoma Susceptibility: A Meta-Analysis of 1564 Cases and 2346 Controls.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Pooled it
  4. N-acetyltransferase 2 genetic variants confer the susceptibility to head and neck carcinoma: evidence from 23 case-control studies.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014
    Pooled it
  5. Article
  6. Global, regional, and national burden and quality of care index of five head and neck cancers: a 32-year longitudinal analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  7. Review
  8. South African speech-language therapists' views on dysphagia in head and neck cancer patients.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2025
    Article
  9. Article
  10. Article
  11. Development ofInternational journal of molecular sciences · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Impact of weight loss on treatment interruption and unplanned hospital admission in head and neck cancer patients undergoing curative (chemo)-radiotherapy in Hong Kong.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  18. Article
  19. Immuno-oncology in head and neck squamous cell carcinoma - a narrative review.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana Lívia Silva GalbiattiResearch Unit for Molecular Biology and Genetics (UPGEM), São José do Rio Preto Medical School, Brazil.
João Armando Padovani-Junior
José Victor Maníglia
Cléa Dometilde Soares Rodrigues
Érika Cristina Pavarino
Eny Maria Goloni-Bertollo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledAlthough head and neck carcinoma ranks fifth among cancer types, patient survival rates have not changed significantly over the past years.

objectiveTo determine the risk factors, causes, therapies, and prevention measures for head and neck cancer.

methodRisk factors, causes, therapies, and preventive measures for this disease were searched on databases PUBMED, MEDLINE, and SCIELO.

resultsAlcohol and tobacco are still atop risk factors. Other factors may influence the development of head and neck carcinoma. Surgery is the main treatment option, and the addition of radiotherapy following surgery is frequent for patients in the early stages of the disease. Other therapies target specific genetic molecular components connected to tumor development. Disease preventive measures include smoking cessation, limiting alcohol intake, preventing exposure to tobacco smoke and environmental carcinogenic agents, early detection of infection by HPV, maintaining oral health, good eating habits, and managing stress.

conclusionAdditional research is needed for a more thorough understanding of the development of head and neck carcinomas and to shed light on new ways to improve therapeutic approaches and interventions.

Indexed as

Head and Neck NeoplasmsHumansRisk Factors

Identifiers

PMID23670332
PMCPMC9443822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.