Evidence map›Paper›PMID 23670195›Full record

ArticleLab on a chip2013

Lab-on-a-chip technologies for single-molecule studies.

Yanhui Zhao, Danqi Chen, Hongjun Yue, Jarrod B French, Joseph Rufo, Stephen J Benkovic, Tony Jun Huang

Abstract read
In one paragraph

Article in Lab on a chip, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Optofluidic wavelength division multiplexing for single-virus detection.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  11. Acoustic force spectroscopy.Nature methods · 2015
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanhui ZhaoDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Danqi Chen
Hongjun Yue
Jarrod B French
Joseph Rufo
Stephen J Benkovic
Tony Jun Huang

Funding

On-Chip Optofluidic Laser Scanning Confocal Microscope for Early Cancer DetectionDP2OD007209 · OD · PENNSYLVANIA STATE UNIVERSITY, THE · PI HUANG, TONY JUN · 2010 to 2010
$2.2M
NIH HHS 1DP2OD007209-01NIH HHS DP2 OD007209
6 · The paper itself

Abstract

Recent developments on various lab-on-a-chip techniques allow miniaturized and integrated devices to perform on-chip single-molecule studies. Fluidic-based platforms that utilize unique microscale fluidic behavior are capable of conducting single-molecule experiments with high sensitivities and throughputs, while biomolecular systems can be studied on-chip using techniques such as DNA curtains, magnetic tweezers, and solid-state nanopores. The advances of these on-chip single-molecule techniques lead to next-generation lab-on-a-chip devices, such as DNA transistors, and single-molecule real-time (SMRT) technology for rapid and low-cost whole genome DNA sequencing. In this Focus article, we will discuss some recent successes in the development of lab-on-a-chip techniques for single-molecule studies and expound our thoughts on the near future of on-chip single-molecule studies.

Indexed as

Lab-On-A-Chip DevicesDNADNA HelicasesMagneticsMicrofluidic Analytical TechniquesMiniaturizationNanoporesPolymerase Chain ReactionProtein BindingDNADNA Helicases

Identifiers

PMID23670195
PMCPMC3955889

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.