Evidence map›Paper›PMID 23670092›Full record

ReviewCell adhesion & migration

Journey to the skin: Somatosensory peripheral axon guidance and morphogenesis.

Fang Wang, Donald P Julien, Alvaro Sagasti

Abstract readReview
In one paragraph

Review in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Morphogenesis of neurons and glia within an epithelium.Development (Cambridge, England) · 2019
    Article
  9. Article
  10. The tactile receptive fields of freely moving Caenorhabditis elegans nematodes.Integrative biology : quantitative biosciences from nano to macro · 2018
    Article
  11. Article
  12. Article
  13. Review
  14. Calpain-Mediated Proteolysis of Talin and FAK Regulates Adhesion Dynamics Necessary for Axon Guidance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  15. Semaphorins and their Signaling Mechanisms.Methods in molecular biology (Clifton, N.J.) · 2017
    Review
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Fang WangDepartment of Molecular, Cell and Developmental Biology; University of California, Los Angeles; Los Angeles, CA USA.
Donald P Julien
Alvaro Sagasti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The peripheral axons of vertebrate tactile somatosensory neurons travel long distances from ganglia just outside the central nervous system to the skin. Once in the skin these axons form elaborate terminals whose organization must be regionally patterned to detect and accurately localize different kinds of touch stimuli. This review describes key studies that identified choice points for somatosensory axon growth cones and the extrinsic molecular cues that function at each of those steps. While much has been learned in the past 20 years about the guidance of these axons, there is still much to be learned about how the peripheral axons of different kinds of somatosensory neurons adopt different trajectories and form specific terminal structures.

Indexed as

AnimalsAxonsGene Expression Regulation, DevelopmentalMorphogenesisSkinaxon guidancedorsal root gangliaLAR receptor phosphataseneurotrophinperipheral axonRohon-BeardsemaphorinSlitsomatosensationtrigeminal

Identifiers

PMID23670092
PMCPMC3739816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.