ReviewNature reviews. Microbiology2013
Antimicrobial activity of metals: mechanisms, molecular targets and applications.
Review in Nature reviews. Microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 748 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
748 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Harnessing plant growth-promoting bacteria for nanoparticle biosynthesis: a systematic review of mechanisms, agricultural applications, and biomedical potential.Bioprocess and biosystems engineering · 2026Pooled it
- Copper-coated carbon nanotube surfaces for inhibiting biofilm formation byCell surface (Amsterdam, Netherlands) · 2026Review
- Review
- Zinc-dependent turnover of ZIP3 transporter mRNA by trypanosome ZNK1.Nucleic acids research · 2026Article
- Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms.Chemical record (New York, N.Y.) · 2026Review
- Regulating xenophagy and phenotype of macrophages by selenium-doped nanoleaves on Zn-based implants for infected bone integration.Bioactive materials · 2026Article
- Next-Generation Hydrogel Skin Adhesives: From Bioinspired Adhesion Chemistry to Regenerative Wound Interfaces.Advanced healthcare materials · 2026Review
- Advancements in pharmaceutical research on traditional Chinese medicine-metal complexes.Journal of pharmaceutical analysis · 2026Review
- Triple Threat: Elucidating Evolution Under Antibiotic, Metal, and Phage Pressure inEcology and evolution · 2026Article
- Exploring chemical space for iridium(iii) complexes: a direct-to-biology (D2B) approach to identifying anticancer and antibacterial agents.Chemical science · 2026Article
- Cobalt and nickel ion synergy promotes gene amplification and stable metal resistance inApplied and environmental microbiology · 2026Article
- A Copper-Complexing Lipid Unmasks the Ethanol Hidden Within Liposomes and Highlights the Relevance of Fabrication Method on the Performance of Lipophilic Functional Molecules.Small science · 2026Article
- A colorimetric sensor array for bacterial identification based on differential etching of T-AgNPs on metal ion-treated cells.Mikrochimica acta · 2026Article
- Sustainable Active Packaging Based on Chitosan-Pomegranate Peel Biofilm Protects Pecorino Romano PDO Cheese Through Polyphenol-Driven Antioxidant and Antimicrobial Activity.Molecules (Basel, Switzerland) · 2026Article
- Transcriptome Profiling ofAntibiotics (Basel, Switzerland) · 2026Article
- Metal-phenolic networks: a promising strategy for cancer immunotherapy.Journal of translational medicine · 2026Review
- Tannic Acid and Copper-Modified ZIF-8 Metal Organic Framework as a Cefotaxime Delivery System for Antimicrobial ActivityTurkish journal of pharmaceutical sciences · 2026Article
- Phage-guided rapid enrichment of copper-protocatechuic acid nanoparticles for targeted antibacterial therapy.Journal of nanobiotechnology · 2026Article
- Contrasts and similarities in the transcriptomic response to antimicrobial coinage metals inMicrobiology spectrum · 2026Article
- Enhancing skin-implant integration in lower-limb transcutaneous prostheses: From interface biology to bioactive, antimicrobial and cell-based strategies.Journal of orthopaedic translation · 2026Review
688 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Metals have been used as antimicrobial agents since antiquity, but throughout most of history their modes of action have remained unclear. Recent studies indicate that different metals cause discrete and distinct types of injuries to microbial cells as a result of oxidative stress, protein dysfunction or membrane damage. Here, we describe the chemical and toxicological principles that underlie the antimicrobial activity of metals and discuss the preferences of metal atoms for specific microbial targets. Interdisciplinary research is advancing not only our understanding of metal toxicity but also the design of metal-based compounds for use as antimicrobial agents and alternatives to antibiotics.
Indexed as
Identifiers
23669886What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.