Evidence map›Paper›PMID 23669450›Full record

ArticleThe Clinical journal of pain2014

Bidirectional associations between pain and physical activity in adolescents.

Jennifer A Rabbitts, Amy Lewandowski Holley, Cynthia W Karlson, Tonya M Palermo

Registry-linked trialAbstract read
In one paragraph

Article in The Clinical journal of pain, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06387758 (Low Systemic/High Local Exercise Load in Pediatric Sickle Cell Disease), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06387758 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Low Systemic/High Local Exercise Load in Pediatric Sickle Cell Disease

TypeinterventionalSponsorUniversity of Mississippi Medical CenterRan2023 to 2025Enrolled60ConditionsSickle Cell Anemia in ChildrenArmsLow systemic strength training, Moderate systemic exercise
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

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  18. Pain is adversely related to weight loss maintenance following bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jennifer A Rabbitts*Department of Anesthesiology and Pain Medicine, Seattle Children's Hospital and University of Washington School of Medicine, Seattle, WA †Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS.
Amy Lewandowski Holley
Cynthia W Karlson
Tonya M Palermo
Seattle Children's Hospital · USUniversity of Mississippi Medical Center · USUniversity of Washington · US

Funding

Sleep-wake disturbances in adolescents with chronic painR01HD053431 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI PALERMO, TONYA M · 2007 to 2011
$1.7M
Innovations in Pediatric Pain ResearchK24HD060068 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI PALERMO, TONYA M · 2009 to 2018
$1.6M
Chronic Pain in Pediatric Primary CareK23HD071946 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI LEWANDOWSKI HOLLEY, AMY S · 2012 to 2016
$583k
NICHD NIH HHS K23 HD071946NICHD NIH HHS K24 HD060068NICHD NIH HHS R01 HD053431NICHD NIH HHS R01HD053431
6 · The paper itself

Abstract

objectivesThe objectives were to: (1) examine temporal relationships between pain and activity in youth, specifically, whether physical activity affects pain intensity and whether intensity of pain affects subsequent physical activity levels on a daily basis, and (2) examine clinical predictors of this relationship.

methodsParticipants were 119 adolescents (59 with chronic pain and 60 healthy) aged 12 to 18 years, 71% female. Adolescents completed 10 days of actigraphic monitoring of physical activity and daily electronic diary recordings of pain intensity, medication use, sleep quality, and mood. Linear mixed models assessed daily associations among physical activity and pain. Daily mean (average count/min) and peak (highest daily level) activity were used for analyses. Medication use, sleep quality, and mood ratings were included as covariates, and age, sex, and body mass index percentile were adjusted for.

resultsHigher pain intensity was associated with lower peak physical activity levels on the next day (t641=-2.25, P=0.03) and greater medication use predicted lower mean physical activity levels the same day (t641=-2.10, P=0.04). Higher mean physical activity levels predicted lower pain intensity ratings at the end of the day (t705=-2.92, P=0.004), but only in adolescents with chronic pain. DISCUSSION: Youth experiencing high pain intensity limit their physical activity level on a day-to-day basis. Activity was related to subsequent pain intensity, and may represent an important focus in chronic pain treatment. Further study of the effect of medications on subsequent activity is needed.

Indexed as

ActigraphyActivities of Daily LivingAdolescentAffectBody Mass IndexChildChronic PainFemaleHumansLinear ModelsMaleMotor ActivityPain MeasurementSelf ReportSleepTime Factors

Identifiers

PMID23669450
PMCPMC3766388
OpenAlexW2021416526

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.