ArticleThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians2013
High correlations in gene expression between paired umbilical cord blood and neonatal blood of healthy newborns on Guthrie cards.
Article in The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- RNA sequencing of archived neonatal dried blood spots.Molecular genetics and metabolism reports · 2017Article
- Psychological resilience and the gene regulatory impact of posttraumatic stress in Nepali child soldiers.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Genome-Wide Profiling of RNA from Dried Blood Spots: Convergence with Bioinformatic Results Derived from Whole Venous Blood and Peripheral Blood Mononuclear Cells.Biodemography and social biology · 2016Article
- Comparison of frozen and unfrozen blood spots for gene expression studies.The Journal of pediatrics · 2014Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveTo examine the correlation in genes expressed in paired umbilical cord blood (UCB) and newborn blood (NB).
methodTotal mRNA and mRNA of three gene sets (inflammatory, hypoxia, and thyroidal response) was assessed using microarray in UCB and NB spotted on Guthrie cards from 7 mother/infant pairs.
resultsThe average gene expression correlation between paired UCB and NB samples was 0.941 when all expressed genes were considered, and 0.949 for three selected gene sets.
conclusionThe high correlation of UCB and NB gene expression suggest that either source may be useful for examining gene expression in the perinatal period.
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Registered trials
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