Evidence map›Paper›PMID 23668538›Full record

ReviewThe Journal of dermatology2013

Modern vitiligo genetics sheds new light on an ancient disease.

Richard A Spritz

Abstract readReview
In one paragraph

Review in The Journal of dermatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Interventions for vitiligo.The Cochrane database of systematic reviews · 2015
    Pooled it
  2. Immunotherapy-induced vitiligo and demyelinating plaques: a case report suggesting a neurocutaneous mechanism.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Review
  4. Article
  5. Aetiopathogenesis of Vitiligo.Dermatology practical & conceptual · 2023
    Review
  6. Granzyme B Gene Polymorphisms Are Associated With Severe Non-segmental Vitiligo.The Journal of clinical and aesthetic dermatology · 2023
    Article
  7. Article
  8. Article
  9. Mechanisms of melanocyte death in vitiligo.Medicinal research reviews · 2021
    Review
  10. Variations inInternational journal of general medicine · 2021
    Article
  11. Mouse Model for Human Vitiligo.Current protocols in immunology · 2019
    Article
  12. Pigmentation and vision: Is GPR143 in control?Journal of neuroscience research · 2019
    Review
  13. Article
  14. Vitiligo: Focus on Clinical Aspects, Immunopathogenesis, and Therapy.Clinical reviews in allergy & immunology · 2018
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Vitiligo and Autoimmune Thyroid Disorders.Frontiers in endocrinology · 2017
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Richard A SpritzHuman Medical Genetics and Genomics Program, University of Colorado School of Medicine, Aurora, Colorado 80045, USA. richard.spritz@ucdenver.edu
University of Colorado Denver · US

Funding

VitGene International Consortium to Identify Susceptibility Genes for GeneralizedR01AR056292 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI SPRITZ, RICHARD ANDREW · 2008 to 2016
$6.9M
Transgenic and Gene Targeting CoreP30AR057212 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI NORRIS, DAVID A. · 2009 to 2018
$6.2M
VitiligoR01AR045584 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI SPRITZ, RICHARD ANDREW · 1999 to 2014
$6.2M
NIAMS NIH HHS P30 AR057212NIAMS NIH HHS P30AR057212NIAMS NIH HHS R01 AR045584NIAMS NIH HHS R01AR045584NIAMS NIH HHS R01 AR056292NIAMS NIH HHS R01AR056292
6 · The paper itself

Abstract

Vitiligo is a complex disorder in which autoimmune destruction of melanocytes results in white patches of skin and overlying hair. Over the past several years, extensive genetic studies have outlined a biological framework of vitiligo pathobiology that underscores its relationship to other autoimmune diseases. This biological framework offers insight into both vitiligo pathogenesis and perhaps avenues towards more effective approaches to treatment and even disease prevention.

Indexed as

HumansMolecular EpidemiologyVitiligo

Identifiers

PMID23668538
PMCPMC3783942
OpenAlexW2024594386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.