Evidence map›Paper›PMID 23668292›Full record

ArticleOrganic letters2013

Attachable solvatochromic fluorophores and bioconjugation studies.

Erica Benedetti, Andrea B E Veliz, Mélanie Charpenay, Laura S Kocsis, Kay M Brummond

Abstract read
In one paragraph

Article in Organic letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Erica BenedettiDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
Andrea B E Veliz
Mélanie Charpenay
Laura S Kocsis
Kay M Brummond
University of Pittsburgh · US

Funding

University of Pittsburgh Center for Chemical DiversityP50GM067082 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WIPF, PETER · 2002 to 2012
$18.6M
NIGMS NIH HHS P50 GM067082NIGMS NIH HHS P50-GM067982
6 · The paper itself

Abstract

The synthesis and utility of attachable cyclopenta[b]naphthalene solvatochromic fluorophores related to Prodan are described. Two fluorophores were selected for functionalization and bioconjugation studies. The skeletons were chemically modified to include reactive functional groups and showed minimal alteration of the optical properties when compared to the parent dyes. The functionalized fluorophores were covalently attached to the carboxyl group of a fatty acid, and azido- and thiol-containing amino acids, demonstrating their potential for labeling biomolecules.

Indexed as

Amino AcidsCyclopentanesFatty AcidsFluorescent DyesMolecular StructureNaphthalenesSolventsSpectrometry, FluorescenceSulfhydryl CompoundsAmino AcidsCyclopentanesFatty AcidsFluorescent DyesnaphthaleneNaphthalenesSolventsSulfhydryl Compounds

Identifiers

PMID23668292
PMCPMC3700427
OpenAlexW2002790099

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.