ArticlePLoS biology2013
Multiplexing stimulus information through rate and temporal codes in primate somatosensory cortex.
Article in PLoS biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.
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Who cites it
92 citing papers in PubMed, 1 synthesis or guideline pooled it, 176 citations in OpenAlex.
- The neural correlates of texture perception: A systematic review and activation likelihood estimation meta-analysis of functional magnetic resonance imaging studies.Brain and behavior · 2023Pooled it
- Spatial and temporal codes mediate the tactile perception of natural textures.Proceedings of the National Academy of Sciences of the United States of America · 2013Trial
- Axonal spike-count regimes link spinal cord stimulation periodicity to artificial sensory detection and discrimination in rodents.bioRxiv : the preprint server for biology · 2026Article
- Contribution of spike timing to the neural code: from fast to slow timescales.Biological cybernetics · 2026Review
- Simultaneous encoding of sensory features: the role of multiplexing and noise in tactile perception and neural representation.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Continuous Vibration-Driven Virtual Tactile Motion Perception Across Fingertips.Sensors (Basel, Switzerland) · 2025Article
- Article
- Survey of temporal coding of sensory information.Frontiers in computational neuroscience · 2025Article
- Encoding of Vibrotactile Stimuli by Mechanoreceptors in Rodent Glabrous Skin.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Disentangling Temporal and Rate Codes in the Primate Somatosensory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Inference of network connectivity from temporally binned spike trains.Journal of neuroscience methods · 2024Article
- Processing the fine-grained features of tactile textures involves the primary somatosensory cortex.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Multiplexing intensity and frequency sensations for artificial touch by modulating temporal features of electrical pulse trains.Frontiers in neuroscience · 2024Article
- Article
- Pre-neuronal processing of haptic sensory cues via dispersive high-frequency vibrational modes.Scientific reports · 2023Article
- Synchrony-Division Neural Multiplexing: An Encoding Model.Entropy (Basel, Switzerland) · 2023Article
- Exploratory evaluation of spinal cord stimulation with dynamic pulse patterns: a promising approach to improve stimulation sensation, coverage of pain areas, and expected pain relief.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Distinctive properties of biological neural networks and recent advances in bottom-up approaches toward a better biologically plausible neural network.Frontiers in computational neuroscience · 2023Review
- Latency correction in sparse neuronal spike trains.Journal of neuroscience methods · 2022Article
- Synaptic reshaping of plastic neuronal networks by periodic multichannel stimulation with single-pulse and burst stimuli.PLoS computational biology · 2022Article
32 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our ability to perceive and discriminate textures relies on the transduction and processing of complex, high-frequency vibrations elicited in the fingertip as it is scanned across a surface. How naturalistic vibrations, and by extension texture, are encoded in the responses of neurons in primary somatosensory cortex (S1) is unknown. Combining single unit recordings in awake macaques and perceptual judgments obtained from human subjects, we show that vibratory amplitude is encoded in the strength of the response evoked in S1 neurons. In contrast, the frequency composition of the vibrations, up to 800 Hz, is not encoded in neuronal firing rates, but rather in the phase-locked responses of a subpopulation of neurons. Moreover, analysis of perceptual judgments suggests that spike timing not only conveys stimulus information but also shapes tactile perception. We conclude that information about the amplitude and frequency of natural vibrations is multiplexed at different time scales in S1, and encoded in the rate and temporal patterning of the response, respectively.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.