Evidence map›Paper›PMID 23666950›Full record

ArticleThe oncologist2013

Multicenter italian experience in liver transplantation for hepatocellular carcinoma in HIV-infected patients.

Fabrizio Di Benedetto, Giuseppe Tarantino, Giorgio Ercolani, Umberto Baccarani, Roberto Montalti, Nicola De Ruvo, Massimiliano Berretta, Gian Luigi Adani, Matteo Zanello, Marcello Tavio and 5 more

Abstract readMulticenter Study
In one paragraph

Article in The oncologist, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fabrizio Di BenedettoLiver and Multivisceral Transplant Center, University of Modena and Reggio Emilia, Modena, Italy. f.diben@virgilio.it
Giuseppe Tarantino
Giorgio Ercolani
Umberto Baccarani
Roberto Montalti
Nicola De Ruvo
Massimiliano Berretta
Gian Luigi Adani
Matteo Zanello
Marcello Tavio
Nicola Cautero
Umberto Tirelli
Antonio D Pinna
Giorgio E Gerunda
Giovanni Guaraldi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of our work is to assess the clinical outcomes of liver transplantation (LT) for hepatocellular carcinoma (HCC) in HIV-coinfected patients. This is a multicenter study involving three Italian transplant centers in northern Italy: University of Modena, University of Bologna, and University of Udine. PATIENTS AND

methodsWe compared 30 HIV-positive patients affected by HCC who underwent LT with 125 HIV-uninfected patients who received the same treatment from September 2004 to June 2009. At listing, there were no differences between HIV-infected and -uninfected patients regarding HCC features. Patients outside the University of California, San Francisco criteria (UCSF) were considered eligible for LT if a down-staging program permitted a reduction of tumor burden.

resultsHIV-infected patients were younger, they were more frequently anti-HCV positive, and a higher number of HIV-infected patients presented a coinfection HBV-HCV. Pre-LT treatments (liver resection and or locoregional treatments) were similar between the two groups. Histological characteristics of the tumor were similar in patients with and without HIV infection. No differences were observed in terms of overall survival and HCC recurrence rates.

conclusionLT for HCC is a feasible procedure and the presence of HIV does not particularly affect the post-LT outcome.

Indexed as

Liver TransplantationAdultAgedCarcinoma, HepatocellularFemaleFollow-Up StudiesHIV-1HIV InfectionsHumansItalyLiver NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalSurvival RateTreatment OutcomeHCVHepatocellular carcinomaHIVLiver transplantation

Identifiers

PMID23666950
PMCPMC3662851

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.