ReviewCurrent neurology and neuroscience reports2013
Health-related quality of life in patients with brain tumors: limitations and additional outcome measures.
Review in Current neurology and neuroscience reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Health-related quality of life in adult patients with brain metastases after stereotactic radiosurgery: a systematic, narrative review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Pooled it
- The use and impact of quality of life assessment tools in clinical care settings for cancer patients, with a particular emphasis on brain cancer: insights from a systematic review and stakeholder consultations.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016Pooled it
- Early palliative care for patients with glioblastoma: A randomized phase III clinical trial (EPCOG).Neuro-oncology · 2026Trial
- The long-term course and relationship with survival of multidimensional fatigue in patients with brain metastases after Gamma Knife radiosurgery.Journal of cancer research and clinical oncology · 2023Trial
- Internet-based guided self-help for glioma patients with depressive symptoms: a randomized controlled trial.Journal of neuro-oncology · 2018Trial
- Post-recurrence management of malignant glial brain tumors: therapeutic strategies, evidence and limitations, palliative care, terminal sedation, and end-of-life considerations.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- Health-related quality of life and its determinants in patients with malignant brain tumors: a prospective longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Neurosurgery Advancements: From Technical Innovation to Patient-Centered Outcomes-A Narrative Review.Journal of clinical medicine · 2026Review
- Neurocognitive impairment and patient-proxy agreement on health-related quality of life evaluations in recurrent high-grade glioma patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Health-Related Quality of Life in Intracranial Meningioma: Current Evidence and Future Directions.Advances in experimental medicine and biology · 2023Article
- Impact of fractionated stereotactic radiotherapy on activity of daily living and performance status in progressive/recurrent glioblastoma: a retrospective study.Radiation oncology (London, England) · 2022Article
- Factors associated with health-related quality of life (HRQoL) deterioration in glioma patients during the progression-free survival period.Neuro-oncology · 2022Article
- Neurocognitive impairment and patient-proxy agreement on health-related quality of life evaluations in recurrent high-grade glioma patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Subjective executive dysfunction in patients with primary brain tumors and their informants: relationships with neurocognitive, psychological, and daily functioning.Brain injury · 2021Article
- Perioperative fatigue in patients with diffuse glioma.Journal of neuro-oncology · 2020Article
- Quality improvement of neuro-oncology services: integrating the routine collection of patient-reported, health-related quality-of-life measures.Neuro-oncology practice · 2019Article
- Moving from clinician-defined to patient-reported outcome measures for survivors of high-grade glioma.Patient related outcome measures · 2019Article
- The Effect of Pet Therapy and Artist Interactions on Quality of Life in Brain Tumor Patients: A Cross-Section of Art and Medicine in Dialog.Behavioral sciences (Basel, Switzerland) · 2018Article
- Development of a questionnaire measuring instrumental activities of daily living (IADL) in patients with brain tumors: a pilot study.Journal of neuro-oncology · 2017Article
- Patient reported endpoints for measuring clinical benefit in (high grade glioma) primary brain tumor patients.Current treatment options in oncology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Health-related quality of life (HRQOL) is a multidimensional concept used to measure patients' functioning and well-being. In recent decades, HRQOL has become an important (secondary) outcome measure in clinical trials for brain tumor patients. It could be questioned, however, whether HRQOL is the only useful outcome measure for assessing the level of functioning and well-being of these patients. As described in this review, several general methodological issues can hamper the interpretation of HRQOL data collected in the oncology setting. Additionally, because brain tumor patients have a progressive brain disease resulting in cognitive impairments, patient-reported outcomes may not always be the most informative and accurate measures of HRQOL in brain tumor patients. Supplementary or alternative measures, such as proxy-rated HRQOL measures and measures of instrumental activities of daily living, may provide a more complete picture of brain tumor patients' functioning in daily life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.