ArticleParasitology research2013
Serological and molecular detection of Strongyloides stercoralis infection among an Orang Asli community in Malaysia.
Article in Parasitology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Systematic Review of Strongyloides stercoralis Infection Diagnosis in Southeast Asia: Insights from Parasitological, Molecular, and Serological Approaches.The American journal of tropical medicine and hygiene · 2024Pooled it
- Prevalence of Strongyloides in Southeast Asia: a systematic review and meta-analysis with implications for public health and sustainable control strategies.Infectious diseases of poverty · 2023Pooled it
- Accuracy of molecular biology techniques for the diagnosis of Strongyloides stercoralis infection-A systematic review and meta-analysis.PLoS neglected tropical diseases · 2018Pooled it
- Article
- High prevalence of Strongyloides stercoralis in people living with HIV: A critical health challenge in the Peruvian Amazon Basin.PLoS neglected tropical diseases · 2025Article
- Entry of Migrant Workers to Malaysia: Consideration to Implement Mass Drug Administration Against Intestinal Parasitic Infections.International journal of health policy and management · 2024Article
- Establishment of an Animal Model Scheme ofPathogens (Basel, Switzerland) · 2023Article
- From past to present: opportunities and trends in the molecular detection and diagnosis of Strongyloides stercoralis.Parasites & vectors · 2023Review
- Seroprevalence and associated risk factors of strongyloidiasis in indigenous communities and healthcare professionals from Brazil.PLoS neglected tropical diseases · 2023Article
- Donor Screening Revisions of Fecal Microbiota Transplantation in Patients with Ulcerative Colitis.Journal of clinical medicine · 2022Article
- Assessing seroprevalence and associated risk factors for multiple infectious diseases in Sabah, Malaysia using serological multiplex bead assays.Frontiers in public health · 2022Article
- Direct detection of Strongyloides infection via molecular and antigen detection methods.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Review
- A Cross-Sectional Study of Seroprevalence of Strongyloidiasis in Pregnant Women (Peruvian Amazon Basin).Pathogens (Basel, Switzerland) · 2020Article
- The investigation of Strongyloides stercoralis seroprevalence in immunosupressed patients in TurkeyTurkish journal of medical sciences · 2019Article
- Molecular and Immnune Diagnosis: Further Testing for Human Strongyloidiasis.Molecular diagnosis & therapy · 2018Article
- Diagnostic performance of urinary IgG antibody detection: A novel approach for population screening of strongyloidiasis.PloS one · 2018Article
- Validation of DESS as a DNA Preservation Method for the Detection of Strongyloides spp. in Canine Feces.International journal of environmental research and public health · 2017Article
- Epidemiological Characteristics of Strongyloidiasis in Inhabitants of Indigenous Communities in Borneo Island, Malaysia.The Korean journal of parasitology · 2016Article
- DIAGNOSIS OF Strongyloides stercoralis INFECTION IN IMMUNOCOMPROMISED PATIENTS BY SEROLOGICAL AND MOLECULAR METHODS.Revista do Instituto de Medicina Tropical de Sao Paulo · 2016Article
- Molecular Diagnostics for Soil-Transmitted Helminths.The American journal of tropical medicine and hygiene · 2016Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detection of Strongyloides stercoralis infection particularly in asymptomatic individuals is often hampered due to the lack of standard diagnostic tools. In this study, the use of serological and molecular approaches were investigated for the detection of S. stercoralis infection among an Orang Asli (indigenous) community following a preliminary detection by microscopic examination of faecal samples. Out of 54 individuals studied, 17/54 (31.5%) were detected to be positive for S. stercoralis infection by enzyme-linked immunosorbent assay (ELISA), compared to 0/54 (0%) by faecal examination. Further confirmation performed by a nested polymerase chain reaction (PCR) using DNA extracted from faecal samples of these 17 individuals yielded 3/17 (17.6%) positives for S. stercoralis DNA amplification. No amplification was seen with the other 37 faecal samples, which were negative by microscopy and ELISA. As the high ELISA positive results were suspected to be false-positives, ELISA is not recommended for use as a detection tool but may be beneficial for evaluating the effectiveness of anti-Strongyloides drugs. The present finding indicated that PCR should be considered as an alternative diagnostic tool for the detection of S. stercoralis infection.
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