ReviewProceedings of the Japan Academy. Series B, Physical and biological sciences2013
Microbial production of isoquinoline alkaloids as plant secondary metabolites based on metabolic engineering research.
Review in Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Transgenic Forsythia plants expressing sesame cytochrome P450 produce beneficial lignans.Scientific reports · 2022Article
- Perspectives and potential applications of endophytic microorganisms in cultivation of medicinal and aromatic plants.Frontiers in plant science · 2022Review
- Production of beneficial lignans in heterologous host plants.Frontiers in plant science · 2022Article
- Full-length transcriptome and metabolite analysis reveal reticuline epimerase-independent pathways for benzylisoquinoline alkaloids biosynthesis inFrontiers in plant science · 2022Article
- Antibacterial Potential and Apoptosis Induction by Pigments from the Endophyte Burkholderia sp. WYAT7.Current microbiology · 2020Article
- Endophytic bacteria: a new source of bioactive compounds.3 Biotech · 2017Review
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Authors and funding
2 authors.
Funding
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Abstract
Plants produce a variety of secondary metabolites that possess strong physiological activities. Unfortunately, however, their production can suffer from a variety of serious problems, including low levels of productivity and heterogeneous quality, as well as difficulty in raw material supply. In contrast, microorganisms can be used to produce their primary and some of their secondary metabolites in a controlled environment, thus assuring high levels of efficiency and uniform quality. In an attempt to overcome the problems associated with secondary metabolite production in plants, we developed a microbial platform for the production of plant isoquinoline alkaloids involving the unification of the microbial and plant metabolic pathways into a single system. The potential applications of this system have also been discussed.
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