ArticleTranscription
The great repression: chromatin and cryptic transcription.
Article in Transcription. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Cryptic transcription in aging.iScience · 2026Review
- When RNA goes off script: ensuring transcript fidelity in transgene expression.The EMBO journal · 2026Review
- Transposable element-gene chimera cartography, origination and role in enhancing transcriptome plasticity.Nature structural & molecular biology · 2026Article
- Transcript diversity in aging: cryptic transcription and splicing.Medical review (2021) · 2025Review
- Growth temperature and chromatinization in archaea.Nature microbiology · 2022Article
- Bacterial Transcription Factors Bind to Coding Regions and Regulate Internal Cryptic Promoters.mBio · 2022Article
- Article
- Loosening chromatin and dysregulated transcription: a perspective on cryptic transcription during mammalian aging.Briefings in functional genomics · 2022Article
- Altered Chromatin States Drive Cryptic Transcription in Aging Mammalian Stem Cells.Nature aging · 2021Article
- Absolute nucleosome occupancy map for theGenome research · 2019Article
- RNA polymerase II-independent recruitment of SPT6L at transcription start sites in Arabidopsis.Nucleic acids research · 2019Article
- Spt6 Is Required for the Fidelity of Promoter Selection.Molecular cell · 2018Article
- Rpp29 regulates histone H3.3 chromatin assembly through transcriptional mechanisms.The Journal of biological chemistry · 2018Article
- Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt- Phenotype and Growth in Saccharomyces cerevisiae.G3 (Bethesda, Md.) · 2016Article
- Highly condensed chromatins are formed adjacent to subtelomeric and decondensed silent chromatin in fission yeast.Nature communications · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The eukaryotic chromatin structure is essential in correctly defining transcription units. Impairing this structure can activate cryptic promoters, and lead to the accumulation of aberrant RNA transcripts. Here we discuss critical pathways that are responsible for the repression of cryptic transcription and the maintenance of genome integrity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.