Evidence map›Paper›PMID 23664778›Full record

ArticleTrends in biotechnology2013

Not-so-incidental findings: the ACMG recommendations on the reporting of incidental findings in clinical whole genome and whole exome sequencing.

Megan Allyse, Marsha Michie

Abstract read
In one paragraph

Article in Trends in biotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Evaluating the resource implications of different service delivery models for offering additional genomic findings.Genetics in medicine : official journal of the American College of Medical Genetics · 2021
    Article
  5. Article
  6. Article
  7. The transformation of medical genetics by clinical genomics: hubris meets humility.Genetics in medicine : official journal of the American College of Medical Genetics · 2019
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Continuing Evolution of Ethical Standards for Genomic Sequencing in Clinical Care: Restoring Patient Choice.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2017
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Economic evidence on identifying clinically actionable findings with whole-genome sequencing: a scoping review.Genetics in medicine : official journal of the American College of Medical Genetics · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Megan AllyseCenter for Biomedical Ethics, 1215 Welch Road, Modular A, Stanford, CA 94305, USA. megand@stanford.edu
Marsha Michie

Funding

Center for Integration of Research on Genetics and EthicsP50HG003389 · NHGRI · STANFORD UNIVERSITY · PI CHO, MILDRED K. · 2004 to 2014
$9.9M
Mapping an ELSI-integrated translational pathway with cell-free fetal DNA testingK99HG006452 · NHGRI · STANFORD UNIVERSITY · PI MICHIE, MARSHA MABRY · 2012 to 2013
$171k
NHGRI NIH HHS K99 HG006452NHGRI NIH HHS P50 HG003389
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ExomeGenomeIncidental FindingsGenomicsGuidelines as TopicMolecular BiologyResearch DesignSequence Analysis, DNAincidental findingsreturning resultswhole genome sequencing

Identifiers

PMID23664778
PMCPMC4086155

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.