ArticleJournal of neuroimmunology2013
Aquaporin 4 molecular mimicry and implications for neuromyelitis optica.
Article in Journal of neuroimmunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Immune Reactivity to Raw and Processed Foods and Their Possible Contributions to Autoimmunity.Foods (Basel, Switzerland) · 2025Review
- Advances in the treatment of neuromyelitis optic spectrum disorder.Therapeutic advances in neurological disorders · 2025Review
- Neuromyelitis optica spectrum disorder after post appendectomy peritonitis: A case report.Radiology case reports · 2024Article
- The Role of Gut Microbiota in Neuromyelitis Optica Spectrum Disorder.International journal of molecular sciences · 2024Review
- The relationship between plasma prolactin levels and clinical manifestations with neuromyelitis optica spectrum disorders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Immune Repertoire Profiling Reveals Its Clinical Application Potential and Triggers for Neuromyelitis Optica Spectrum Disorders.Neurology(R) neuroimmunology & neuroinflammation · 2023Article
- The prevalence of IgG antibodies against milk and milk antigens in patients with multiple sclerosis.Frontiers in immunology · 2023Article
- GANAB andInternational journal of molecular sciences · 2022Review
- Microbial dysbiosis in the gut drives systemic autoimmune diseases.Frontiers in immunology · 2022Review
- The Role of Exposomes in the Pathophysiology of Autoimmune Diseases I: Toxic Chemicals and Food.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021Review
- Reaction of Lectin-Specific Antibody with Human Tissue: Possible Contributions to Autoimmunity.Journal of immunology research · 2020Article
- Reaction of antibodies toWorld journal of gastroenterology · 2019Article
- Plant and human aquaporins: pathogenesis from gut to brain.Immunologic research · 2019Review
- Amyloid-Beta 1-42 Cross-Reactive Antibody Prevalent in Human Sera May Contribute to Intraneuronal Deposition of A-Beta-P-42.International journal of Alzheimer's disease · 2018Article
- The Gut Microbiome in Neuromyelitis Optica.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2018Review
- The Role of Brain-Reactive Autoantibodies in Brain Pathology and Cognitive Impairment.Frontiers in immunology · 2017Review
- Detection of Antibodies against Human and Plant Aquaporins in Patients with Multiple Sclerosis.Autoimmune diseases · 2015Article
- Acute myelopathy or cauda equina syndrome in HIV-positive adults in a tuberculosis endemic setting: MRI, clinical, and pathologic findings.AJNR. American journal of neuroradiology · 2014Article
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Neuromyelitis optica (NMO) is associated with antibodies to aquaporin 4 (AQP4). We hypothesized that antibodies to AQP4 can be triggered by exposure to environmental proteins. We compared human AQP4 to plant and bacterial proteins to investigate the occurrence of significantly similar structures and sequences. High similarity to a known epitope for NMO-IgG, AQP4(207-232), was observed for corn ZmTIP4-1. NMO and non-NMO sera were assessed for reactivity to AQP4(207-232) and the corn peptide. NMO patient serum showed reactivity to both peptides as well as to plant tissue. These findings warrant further investigation into the role of the environment in NMO etiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.