ArticleBMC genomics2013
Physiological stressors and invasive plant infections alter the small RNA transcriptome of the rice blast fungus, Magnaporthe oryzae.
Article in BMC genomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 60 citations in OpenAlex.
- Deciphering the Contribution of TATA Box and 5'UTR to Defense Signaling in Rice Under Blast Infection.Biology · 2025Review
- Epigenetic modulation of fungal pathogens: a focus onFrontiers in microbiology · 2024Review
- Extracellular RNAs released by plant-associated fungi: from fundamental mechanisms to biotechnological applications.Applied microbiology and biotechnology · 2023Review
- Magnaporthe oryzae Chloroplast Targeting Endo-β-1,4-Xylanase I MoXYL1A Regulates Conidiation, Appressorium Maturation and Virulence of the Rice Blast Fungus.Rice (New York, N.Y.) · 2022Article
- Understanding the Dynamics of Blast Resistance in Rice-Journal of fungi (Basel, Switzerland) · 2022Review
- Exploring the Effectiveness and Durability of Trans-Kingdom Silencing of Fungal Genes in the Vascular PathogenInternational journal of molecular sciences · 2022Article
- The ectomycorrhizal fungusProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Exploring the Common Mechanism of Fungal sRNA Transboundary Regulation of Plants Based on Ensemble Learning Methods.Frontiers in genetics · 2022Article
- Comparative profiling of canonical and non-canonical small RNAs in the rice blast fungus,Frontiers in microbiology · 2022Article
- Role of Dicer-Dependent RNA Interference in Regulating Mycoparasitic Interactions.Microbiology spectrum · 2021Article
- Contribution of Small RNA Pathway to Interactions of Rice with Pathogens and Insect Pests.Rice (New York, N.Y.) · 2021Review
- Comparative Analysis of Transcriptome and sRNAs Expression Patterns in theInternational journal of molecular sciences · 2021Article
- A Novel DCL2-Dependent Micro-Like RNAFrontiers in microbiology · 2021Article
- Construction of sRNA Regulatory Network forFrontiers in genetics · 2021Article
- MicroRNA-like milR236, regulated by transcription factor MoMsn2, targets histone acetyltransferase MoHat1 to play a role in appressorium formation and virulence of the rice blast fungus Magnaporthe oryzae.Fungal genetics and biology : FG & B · 2020Article
- MiningFrontiers in genetics · 2019Article
- A fungal Argonaute interferes with RNA interference.Nucleic acids research · 2018Article
- Epigenetic regulation of development and pathogenesis in fungal plant pathogens.Molecular plant pathology · 2017Review
- Genome-wide exonic small interference RNA-mediated gene silencing regulates sexual reproduction in the homothallic fungus Fusarium graminearum.PLoS genetics · 2017Article
- Are We Eating Our Way to Prostate Cancer-A Hypothesis Based on the Evolution, Bioaccumulation, and Interspecific Transfer of miR-150.Non-coding RNA · 2016Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe rice blast fungus, Magnaporthe oryzae is a destructive pathogen of rice and other related crops, causing significant yield losses worldwide. Endogenous small RNAs (sRNAs), including small interfering RNAs (siRNAs) and microRNAs (miRNAs) are critical components of gene regulation in many eukaryotic organisms. Recently several new species of sRNAs have been identified in fungi. This fact along with the availability of genome sequence makes M. oryzae a compelling target for sRNA profiling. We have examined sRNA species and their biosynthetic genes in M. oryzae, and the degree to which these elements regulate fungal stress responses. To this end, we have characterized sRNAs under different physiological stress conditions, which had not yet been examined in this fungus.
resultsThe resulting libraries are composed of more than 37 million total genome matched reads mapping to intergenic regions, coding sequences, retrotransposons, inverted, tandem, and other repeated regions of the genome with more than half of the small RNAs arising from intergenic regions. The 24 nucleotide (nt) size class of sRNAs was predominant. A comparison to transcriptional data of M. oryzae undergoing the same physiological stresses indicates that sRNAs play a role in transcriptional regulation for a small subset of genes. Support for this idea comes from generation and characterization of mutants putatively involved in sRNAs biogenesis; our results indicate that the deletion of Dicer-like genes and an RNA-Dependent RNA Polymerase gene increases the transcriptional regulation of this subset of genes, including one involved in virulence.
conclusionsVarious physiological stressors and in planta conditions alter the small RNA profile of the rice blast fungus. Characterization of sRNA biosynthetic mutants helps to clarify the role of sRNAs in transcriptional control.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.