Evidence map›Paper›PMID 23663431›Full record

ReviewJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2013

Convergence of two major pathophysiologic mechanisms in nasal polyposis: immune response to Staphylococcus aureus and airway remodeling.

Rogério Pezato, Leonardo Balsalobre, Milena Lima, Thiago F P Bezerra, Richard L Voegels, Luis Carlos Gregório, Aldo Cassol Stamm, Thibaut van Zele

Open access · goldAbstract readReview
In one paragraph

Review in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Differential Angiogenic Induction Impacts Nasal Polyp Tissue Growth.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  2. Article
  3. Article
  4. BMP-7, MMP-9, and TGF-β tissue remodeling proteins and their correlations with interleukins 6 and 10 in chronic rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Observational
  5. Can the sensitisation to staphylococcal enterotoxin predict the severity of chronic rhinosinusitis?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  6. Sinonasal Tissue Remodelling during Chronic Rhinosinusitis.International journal of otolaryngology · 2021
    Review
  7. Article
  8. Article
  9. IL-5 and IL-6 are increased in the frontal recess of eosinophilic chronic rhinosinusitis patients.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2017
    Article
  10. Article
  11. Article
  12. Remodeling and Repair in Rhinosinusitis.Current allergy and asthma reports · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Rogério PezatoDepartment of Otolaryngology - Head and Neck Surgery of Federal University of São Paulo, Rua Maestro Antão Fernandes, 173, Jd São Bento, São Paulo, SP02526-060, Brazil. pezatobau@ig.com.br.
Leonardo Balsalobre
Milena Lima
Thiago F P Bezerra
Richard L Voegels
Luis Carlos Gregório
Aldo Cassol Stamm
Thibaut van Zele
Universidade Federal de São Paulo · BRGhent University Hospital · BEUniversidade de São Paulo · BRHospital São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review is addressed two pathophysiologic mechanisms implicated in the pathogenesis of nasal polyposis: the unique remodeling process found in nasal polyp tissue and the immune response of patients with nasal polyposis to Staphylococcus aureus. These two theories converge to the same direction in different aspects, including decreased extracellular matrix production, impaired T regulation and favoring of a Th2 immune response.In patients with nasal polyposis, an exaggerated immune response to Staphylococcus aureus may aggravate the airway remodeling process.

Indexed as

Airway RemodelingHumansImmunoglobulin EMatrix Metalloproteinase 7Matrix Metalloproteinase 9Nasal PolypsRhinitisSinusitisStaphylococcus aureusSuperantigensTransforming Growth Factor beta1Immunoglobulin EMatrix Metalloproteinase 7Matrix Metalloproteinase 9SuperantigensTransforming Growth Factor beta1

Identifiers

PMID23663431
PMCPMC3651231
OpenAlexW2119214944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.