ArticleCurrent pathobiology reports2013
Generation of Lung Epithelium from Pluripotent Stem Cells.
Article in Current pathobiology reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed.
- Organoid for Air Pollution Toxicity Assessment: Advances and Environmental Applicability.Environment & health (Washington, D.C.) · 2025Review
- Modeling of Respiratory Diseases Evolving with Fibrosis from Organoids Derived from Human Pluripotent Stem Cells.International journal of molecular sciences · 2023Review
- Developing Bottom-Up Induced Pluripotent Stem Cell Derived Solid Tumor Models Using Precision Genome Editing Technologies.The CRISPR journal · 2022Review
- National Heart, Lung, and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop Report: Moving Forward in Lung Regeneration.American journal of respiratory cell and molecular biology · 2021Article
- miR-200 family expression during normal and abnormal lung development due to congenital diaphragmatic hernia at the later embryonic stage in the nitrofen rat model.Pediatric surgery international · 2020Article
- Stem cells and lung regeneration.American journal of physiology. Cell physiology · 2020Review
- Application of iPSC to Modelling of Respiratory Diseases.Advances in experimental medicine and biology · 2020Review
- Radiation Induces Pulmonary Fibrosis by Promoting the Fibrogenic Differentiation of Alveolar Stem Cells.Stem cells international · 2020Article
- Stimulatory Secretions of Airway Epithelial Cells Accelerate Early Repair of Tracheal Epithelium.Scientific reports · 2017Article
- BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity.American journal of physiology. Lung cellular and molecular physiology · 2017Article
- Hypoxia enhances differentiation of mouse embryonic stem cells into definitive endoderm and distal lung cells.Stem cells and development · 2015Article
- Induced pluripotent stem cells and their use in cardiac and neural regenerative medicine.International journal of molecular sciences · 2015Review
- Efficient intratracheal delivery of airway epithelial cells in mice and pigs.American journal of physiology. Lung cellular and molecular physiology · 2015Article
- A Molecular atlas of Xenopus respiratory system development.Developmental dynamics : an official publication of the American Association of Anatomists · 2015Article
- Gene regulatory networks governing lung specification.Journal of cellular biochemistry · 2014Review
- Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The understanding of key processes and signaling mechanisms in lung development has been mainly demonstrated through gain and loss of function studies in mice, while human lung development remains largely unexplored due to inaccessibility. Several recent reports have exploited the identification of key signaling mechanisms that regulate lineage commitment and restriction in mouse lung development, to direct differentiation of both mouse and human pluripotent stem cells towards lung epithelial cells. In this review, we discuss the recent advances in the generation of respiratory epithelia from pluripotent stem cells and the potential of these engineered cells for novel scientific discoveries in lung diseases and future translation into regenerative therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.