ArticleNigerian medical journal : journal of the Nigeria Medical Association2013
Is there any relationship between Chlamydophila pneumoniae and coronary atherosclerosis among Iranians?
Article in Nigerian medical journal : journal of the Nigeria Medical Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Bacterial infections are associated with cardiovascular disease in Iran: a meta-analysis.Archives of medical science : AMS · 2019Article
- Infectious and coronary artery disease.ARYA atherosclerosis · 2016Review
- Association of Chlamydia pneumoniae Infection With Atherosclerotic Plaque Formation.Global journal of health science · 2015Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtherosclerosis is a coronary heart disease, andis the most common cause of death in the industrialized world. Some studies suggested that atherosclerosis may be triggered by infectious agents, mostly Chlamydophila pneumoniae. However, the role of C. pneumoniae in the pathogenesis of coronary atherosclerosis is still controversial.
objectivesThis study was performed to evaluate whether there is a significant association between coronary artery atherosclerosis and C. pneumoniae by the polymerase chain reaction (PCR) method. MATERIALS AND
methodsThis case-control study was carried out on formalin-fixed paraffin-embedded tissue biopsies of the coronary arteries obtained from 30 patients with coronary atherosclerosis and 30 subjects without atherosclerosis living in Northeast of Iran. All subjects' weight and height were determined, and the body mass index was calculated. We also reviewed the medical history and previous laboratory reports of patients. Deoxyribonucleic acid (DNA) was extracted, and C. pneumonia DNA was amplified and detected using PCR assay.
resultsThe age of the patients in the study group was from 18 to 50 years, and the male to female ratio was 5:1. Only oneout of the 30 coronary tissue samples had positive PCR for C. pneumoniae (3.3%), while it was negative for patients in the control group.
conclusionsThis study showed that C. pneumoniae infection is not strongly associated with coronary artery atherosclerosis in Northeast of Iran.
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