ArticleMolecules and cells2013
Requirement of vesicle-associated membrane protein 721 and 722 for sustained growth during immune responses in Arabidopsis.
Article in Molecules and cells, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 61 citations in OpenAlex.
- Molecular choreography of vesicle trafficking: Exocyst-SNARE interplay in plant defense.Journal of advanced research · 2026Review
- SYNTAXIN OF PLANTS132 Regulates Root Meristem Activity and Stem Cell Niche Maintenance via RGF-PLT Pathways.International journal of molecular sciences · 2025Article
- The Arabidopsis SNARE complex genes regulate the early stages of pollen-stigma interactions.Plant reproduction · 2024Article
- The SYP123-VAMP727 SNARE complex delivers secondary cell wall components for root hair shank hardening in Arabidopsis.The Plant cell · 2023Article
- A bacterial type III effector targets plant vesicle-associated membrane proteins.Molecular plant pathology · 2023Article
- Transcriptomic Profiling Highlights the ABA Response Role ofInternational journal of molecular sciences · 2023Article
- VAMP724 and VAMP726 are involved in autophagosome formation inAutophagy · 2023Article
- TaSYP137 and TaVAMP723, the SNAREs Proteins from Wheat, Reduce Resistance toInternational journal of molecular sciences · 2023Article
- Rab GTPases, tethers, and SNAREs work together to regulateFrontiers in plant science · 2023Review
- Synaptotagmin 4 and 5 additively contribute to Arabidopsis immunity toPlant signaling & behavior · 2022Article
- RAB GTPases and SNAREs at the trans-Golgi network in plants.Journal of plant research · 2022Review
- Proteomics and Co-expression Network Analysis Reveal the Importance of Hub Proteins and Metabolic Pathways in Nicotine Synthesis and Accumulation in Tobacco (Frontiers in plant science · 2022Article
- SNAREs Regulate Vesicle Trafficking During Root Growth and Development.Frontiers in plant science · 2022Review
- Synaptotagmin 5 Controls SYP132-VAMP721/722 Interaction for Arabidopsis Immunity toMolecules and cells · 2021Article
- The vesicular trafficking system component MIN7 is required for minimizing Fusarium graminearum infection.Journal of experimental botany · 2021Article
- The Arabidopsis R-SNARE VAMP714 is essential for polarisation of PIN proteins and auxin responses.The New phytologist · 2021Article
- Genetic Dissection Uncovers Genome-Wide Marker-Trait Associations for Plant Growth, Yield, and Yield-Related Traits Under Varying Nitrogen Levels in Nested Synthetic Wheat Introgression Libraries.Frontiers in plant science · 2021Article
- SNAREs in Plant Biotic and Abiotic Stress Responses.Molecules and cells · 2020Review
- Vesicle Transport in Plants: A Revised Phylogeny of SNARE Proteins.Evolutionary bioinformatics online · 2020Article
- Regulation of cellular VAMP721/722 abundance in arabidopsis.Plant signaling & behavior · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracellular immune responses to ascomycete and oomycete pathogens in Arabidopsis are dependent on vesicle-associated secretion mediated by the SNARE proteins PEN1 syntaxin, SNAP33 and endomembrane-resident VAMP721/722. Continuous movement of functional GFP-VAMP722 to and from the plasma membrane in non-stimulated cells reflects the second proposed function of VAMP721/722 in constitutive secretion during plant growth and development. Application of the bacterium-derived elicitor flg22 stabilizes VAMP721/722 that are otherwise constitutively degraded via the 26S proteasome pathway. Depletion of VAMP721/722 levels by reducing VAMP721/722 gene dosage enhances flg22-induced seedling growth inhibition in spite of elevated VAMP721/722 abundance. We therefore propose that plants prioritize the deployment of the corresponding secretory pathway for defense over plant growth. Interstingly, VAMP721/722 specifically interact in vitro and in vivo with the plasma membrane syntaxin SYP132 that is required for plant growth and resistance to bacteria. This suggests that the plant growth/immunity-involved VAMP721/722 form SNARE complexes with multiple plasma membrane syntaxins to discharge cue-dependent cargo molecules.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.